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Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis.
Zhang Y, Li Y, Thompson KN, Stoletov K, Yuan Q, Bera K, Lee SJ, Zhao R, Kiepas A, Wang Y, Mistriotis P, Serra SA, Lewis JD, Valverde MA, Martin SS, Sun SX, Konstantopoulos K. Zhang Y, et al. Nat Commun. 2022 Oct 17;13(1):6128. doi: 10.1038/s41467-022-33683-1. Nat Commun. 2022. PMID: 36253369 Free PMC article.
Sculpting Rupture-Free Nuclear Shapes in Fibrous Environments.
Jana A, Tran A, Gill A, Kiepas A, Kapania RK, Konstantopoulos K, Nain AS. Jana A, et al. Adv Sci (Weinh). 2022 Sep;9(25):e2203011. doi: 10.1002/advs.202203011. Epub 2022 Jul 21. Adv Sci (Weinh). 2022. PMID: 35863910 Free PMC article.
Migration and 3D Traction Force Measurements inside Compliant Microchannels.
Afthinos A, Bera K, Chen J, Ozcelikkale A, Amitrano A, Choudhury MI, Huang R, Pachidis P, Mistriotis P, Chen Y, Konstantopoulos K. Afthinos A, et al. Nano Lett. 2022 Sep 28;22(18):7318-7327. doi: 10.1021/acs.nanolett.2c01261. Epub 2022 Sep 15. Nano Lett. 2022. PMID: 36112517 Free PMC article.
The fluid shear stress sensor TRPM7 regulates tumor cell intravasation.
Yankaskas CL, Bera K, Stoletov K, Serra SA, Carrillo-Garcia J, Tuntithavornwat S, Mistriotis P, Lewis JD, Valverde MA, Konstantopoulos K. Yankaskas CL, et al. Sci Adv. 2021 Jul 9;7(28):eabh3457. doi: 10.1126/sciadv.abh3457. Print 2021 Jul. Sci Adv. 2021. PMID: 34244134 Free PMC article.