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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2020 | 1 |
2021 | 1 |
2022 | 1 |
2023 | 2 |
2024 | 2 |
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7 results
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Page 1
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Blood. 2023 May 11;141(19):2372-2389. doi: 10.1182/blood.2022018428.
Blood. 2023.
PMID: 36580665
Free PMC article.
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC, Nguyen HD.
Liu ZS, et al.
Cancer Res. 2024 Feb 15;84(4):577-597. doi: 10.1158/0008-5472.CAN-23-3239.
Cancer Res. 2024.
PMID: 37967363
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TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.
Maifrede S, Le BV, Nieborowska-Skorska M, Golovine K, Sullivan-Reed K, Dunuwille WMB, Nacson J, Hulse M, Keith K, Madzo J, Caruso LB, Gazze Z, Lian Z, Padella A, Chitrala KN, Bartholdy BA, Matlawska-Wasowska K, Di Marcantonio D, Simonetti G, Greiner G, Sykes SM, Valent P, Paietta EM, Tallman MS, Fernandez HF, Litzow MR, Minden MD, Huang J, Martinelli G, Vassiliou GS, Tempera I, Piwocka K, Johnson N, Challen GA, Skorski T.
Maifrede S, et al.
Cancer Res. 2021 Oct 1;81(19):5089-5101. doi: 10.1158/0008-5472.CAN-20-3761. Epub 2021 Jul 2.
Cancer Res. 2021.
PMID: 34215619
Free PMC article.
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Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination-Deficient Leukemia Cells.
Sullivan-Reed K, Toma MM, Drzewiecka M, Nieborowska-Skorska M, Nejati R, Karami A, Wasik MA, Sliwinski T, Skorski T.
Sullivan-Reed K, et al.
Mol Cancer Res. 2023 Oct 2;21(10):1017-1022. doi: 10.1158/1541-7786.MCR-22-1035.
Mol Cancer Res. 2023.
PMID: 37358557
Free PMC article.
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Clonal medicine targeting DNA damage response eradicates leukemia.
Toma MM, Karami A, Nieborowska-Skorska M, Chirtala KN, Pepek M, Hadzijusufovic E, Stoklosa T, Valent P, Skorski T.
Toma MM, et al.
Leukemia. 2024 Mar;38(3):671-675. doi: 10.1038/s41375-024-02138-5. Epub 2024 Jan 16.
Leukemia. 2024.
PMID: 38228681
Free PMC article.
No abstract available.
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Pre-Existing and Acquired Resistance to PARP Inhibitor-Induced Synthetic Lethality.
Le BV, Podszywałow-Bartnicka P, Piwocka K, Skorski T.
Le BV, et al.
Cancers (Basel). 2022 Nov 24;14(23):5795. doi: 10.3390/cancers14235795.
Cancers (Basel). 2022.
PMID: 36497275
Free PMC article.
Review.
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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.
Le BV, Podszywalow-Bartnicka P, Maifrede S, Sullivan-Reed K, Nieborowska-Skorska M, Golovine K, Yao JC, Nejati R, Cai KQ, Caruso LB, Swatler J, Dabrowski M, Lian Z, Valent P, Paietta EM, Levine RL, Fernandez HF, Tallman MS, Litzow MR, Huang J, Challen GA, Link D, Tempera I, Wasik MA, Piwocka K, Skorski T.
Le BV, et al.
Cell Rep. 2020 Oct 6;33(1):108221. doi: 10.1016/j.celrep.2020.108221.
Cell Rep. 2020.
PMID: 33027668
Free PMC article.
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