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2020 3
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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Targeting telomerase for cancer therapy.
Guterres AN, Villanueva J. Guterres AN, et al. Oncogene. 2020 Sep;39(36):5811-5824. doi: 10.1038/s41388-020-01405-w. Epub 2020 Jul 30. Oncogene. 2020. PMID: 32733068 Free PMC article. Review.
The MEK/ERK Network as a Therapeutic Target in Human Cancer.
Barbosa R, Acevedo LA, Marmorstein R. Barbosa R, et al. Mol Cancer Res. 2021 Mar;19(3):361-374. doi: 10.1158/1541-7786.MCR-20-0687. Epub 2020 Nov 2. Mol Cancer Res. 2021. PMID: 33139506 Free PMC article. Review.
Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling.
Nguyen D, Lin LY, Zhou JO, Kibby E, Sia TW, Tillis TD, Vapuryan N, Xu MR, Potluri R, Shin Y, Erler EA, Bronkema N, Boehlmer DJ, Chung CD, Burkhard C, Zeng SH, Grasso M, Acevedo LA, Marmorstein R, Fera D. Nguyen D, et al. Biochemistry. 2020 Dec 22;59(50):4755-4765. doi: 10.1021/acs.biochem.0c00598. Epub 2020 Dec 3. Biochemistry. 2020. PMID: 33272017 Free PMC article.