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2015 1
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2019 3
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19 results

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Page 1
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.
Mateo J, Carreira S, Sandhu S, Miranda S, Mossop H, Perez-Lopez R, Nava Rodrigues D, Robinson D, Omlin A, Tunariu N, Boysen G, Porta N, Flohr P, Gillman A, Figueiredo I, Paulding C, Seed G, Jain S, Ralph C, Protheroe A, Hussain S, Jones R, Elliott T, McGovern U, Bianchini D, Goodall J, Zafeiriou Z, Williamson CT, Ferraldeschi R, Riisnaes R, Ebbs B, Fowler G, Roda D, Yuan W, Wu YM, Cao X, Brough R, Pemberton H, A'Hern R, Swain A, Kunju LP, Eeles R, Attard G, Lord CJ, Ashworth A, Rubin MA, Knudsen KE, Feng FY, Chinnaiyan AM, Hall E, de Bono JS. Mateo J, et al. N Engl J Med. 2015 Oct 29;373(18):1697-708. doi: 10.1056/NEJMoa1506859. N Engl J Med. 2015. PMID: 26510020 Free PMC article. Clinical Trial.
Cancer and the Circadian Clock.
Shafi AA, Knudsen KE. Shafi AA, et al. Cancer Res. 2019 Aug 1;79(15):3806-3814. doi: 10.1158/0008-5472.CAN-19-0566. Epub 2019 Jul 12. Cancer Res. 2019. PMID: 31300477 Free PMC article. Review.
Relevance of pRB Loss in Human Malignancies.
Mandigo AC, Tomlins SA, Kelly WK, Knudsen KE. Mandigo AC, et al. Clin Cancer Res. 2022 Jan 15;28(2):255-264. doi: 10.1158/1078-0432.CCR-21-1565. Epub 2021 Aug 18. Clin Cancer Res. 2022. PMID: 34407969 Free PMC article. Review.
Linking DNA Damage and Hormone Signaling Pathways in Cancer.
Schiewer MJ, Knudsen KE. Schiewer MJ, et al. Trends Endocrinol Metab. 2016 Apr;27(4):216-225. doi: 10.1016/j.tem.2016.02.004. Epub 2016 Mar 1. Trends Endocrinol Metab. 2016. PMID: 26944914 Free PMC article. Review.
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes.
McCann JJ, Vasilevskaya IA, McNair C, Gallagher P, Neupane NP, de Leeuw R, Shafi AA, Dylgjeri E, Mandigo AC, Schiewer MJ, Knudsen KE. McCann JJ, et al. Oncogene. 2022 Jan;41(3):444-458. doi: 10.1038/s41388-021-01903-5. Epub 2021 Nov 12. Oncogene. 2022. PMID: 34773073 Free PMC article.
PARP-1 regulates DNA repair factor availability.
Schiewer MJ, Mandigo AC, Gordon N, Huang F, Gaur S, de Leeuw R, Zhao SG, Evans J, Han S, Parsons T, Birbe R, McCue P, McNair C, Chand SN, Cendon-Florez Y, Gallagher P, McCann JJ, Poudel Neupane N, Shafi AA, Dylgjeri E, Brand LJ, Visakorpi T, Raj GV, Lallas CD, Trabulsi EJ, Gomella LG, Dicker AP, Kelly WK, Leiby BE, Knudsen B, Feng FY, Knudsen KE. Schiewer MJ, et al. EMBO Mol Med. 2018 Dec;10(12):e8816. doi: 10.15252/emmm.201708816. EMBO Mol Med. 2018. PMID: 30467127 Free PMC article.
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.
Shafi AA, McNair CM, McCann JJ, Alshalalfa M, Shostak A, Severson TM, Zhu Y, Bergman A, Gordon N, Mandigo AC, Chand SN, Gallagher P, Dylgjeri E, Laufer TS, Vasilevskaya IA, Schiewer MJ, Brunner M, Feng FY, Zwart W, Knudsen KE. Shafi AA, et al. Nat Commun. 2021 Jan 15;12(1):401. doi: 10.1038/s41467-020-20513-5. Nat Commun. 2021. PMID: 33452241 Free PMC article.
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies.
Dylgjeri E, McNair C, Goodwin JF, Raymon HK, McCue PA, Shafi AA, Leiby BE, de Leeuw R, Kothari V, McCann JJ, Mandigo AC, Chand SN, Schiewer MJ, Brand LJ, Vasilevskaya I, Gordon N, Laufer TS, Gomella LG, Lallas CD, Trabulsi EJ, Feng FY, Filvaroff EH, Hege K, Rathkopf D, Knudsen KE. Dylgjeri E, et al. Clin Cancer Res. 2019 Sep 15;25(18):5623-5637. doi: 10.1158/1078-0432.CCR-18-2207. Epub 2019 Jul 2. Clin Cancer Res. 2019. PMID: 31266833 Free PMC article.
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.
Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG. Urbanucci A, et al. Cell Rep. 2017 Jun 6;19(10):2045-2059. doi: 10.1016/j.celrep.2017.05.049. Cell Rep. 2017. PMID: 28591577 Free PMC article.
19 results