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Page 1
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury.
Brightwell CR, Latham CM, Keeble AR, Thomas NT, Owen AM, Reeves KA, Long DE, Patrick M, Gonzalez-Velez S, Abed V, Annamalai RT, Jacobs C, Conley CE, Hawk GS, Stone AV, Fry JL, Thompson KL, Johnson DL, Noehren B, Fry CS. Brightwell CR, et al. Sci Adv. 2023 Dec;9(48):eadi9134. doi: 10.1126/sciadv.adi9134. Epub 2023 Nov 29. Sci Adv. 2023. PMID: 38019905 Free PMC article.
Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis.
Brightwell CR, Kulkarni AS, Paredes W, Zhang K, Perkins JB, Gatlin KJ, Custodio M, Farooq H, Zaidi B, Pai R, Buttar RS, Tang Y, Melamed ML, Hostetter TH, Pessin JE, Hawkins M, Fry CS, Abramowitz MK. Brightwell CR, et al. JCI Insight. 2021 Dec 22;6(24):e150112. doi: 10.1172/jci.insight.150112. JCI Insight. 2021. PMID: 34784301 Free PMC article.
Thermal injury initiates pervasive fibrogenesis in skeletal muscle.
Brightwell CR, Hanson ME, El Ayadi A, Prasai A, Wang Y, Finnerty CC, Fry CS. Brightwell CR, et al. Am J Physiol Cell Physiol. 2020 Aug 1;319(2):C277-C287. doi: 10.1152/ajpcell.00337.2019. Epub 2020 May 20. Am J Physiol Cell Physiol. 2020. PMID: 32432932 Free PMC article.
17 results