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Year Number of Results
2018 3
2019 1
2020 1
2021 3
2022 5
2023 5
2024 1

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17 results

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Page 1
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.
Michelet X, Dyck L, Hogan A, Loftus RM, Duquette D, Wei K, Beyaz S, Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, Nikolajczyk BS, Mills KHG, Brenner MB, Finlay D, Lynch L. Michelet X, et al. Nat Immunol. 2018 Dec;19(12):1330-1340. doi: 10.1038/s41590-018-0251-7. Epub 2018 Nov 12. Nat Immunol. 2018. PMID: 30420624
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.
Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG. Wu D, et al. Nature. 2018 Jul;559(7715):637-641. doi: 10.1038/s41586-018-0350-5. Epub 2018 Jul 18. Nature. 2018. PMID: 30022161 Free PMC article.
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments.
Lopes N, McIntyre C, Martin S, Raverdeau M, Sumaria N, Kohlgruber AC, Fiala GJ, Agudelo LZ, Dyck L, Kane H, Douglas A, Cunningham S, Prendeville H, Loftus R, Carmody C, Pierre P, Kellis M, Brenner M, Argüello RJ, Silva-Santos B, Pennington DJ, Lynch L. Lopes N, et al. Nat Immunol. 2021 Feb;22(2):179-192. doi: 10.1038/s41590-020-00848-3. Epub 2021 Jan 18. Nat Immunol. 2021. PMID: 33462452 Free PMC article.
Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function.
Dyck L, Prendeville H, Raverdeau M, Wilk MM, Loftus RM, Douglas A, McCormack J, Moran B, Wilkinson M, Mills EL, Doughty M, Fabre A, Heneghan H, LeRoux C, Hogan A, Chouchani ET, O'Shea D, Brennan D, Lynch L. Dyck L, et al. J Exp Med. 2022 Mar 7;219(3):e20210042. doi: 10.1084/jem.20210042. Epub 2022 Feb 1. J Exp Med. 2022. PMID: 35103755 Free PMC article.
Interleukin-17 as a key player in neuroimmunometabolism.
Douglas A, Stevens B, Lynch L. Douglas A, et al. Nat Metab. 2023 Jul;5(7):1088-1100. doi: 10.1038/s42255-023-00846-3. Epub 2023 Jul 20. Nat Metab. 2023. PMID: 37488456 Free PMC article. Review.
Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET. Mills EL, et al. Cell Metab. 2022 Jan 4;34(1):140-157.e8. doi: 10.1016/j.cmet.2021.11.003. Epub 2021 Dec 2. Cell Metab. 2022. PMID: 34861155 Free PMC article.
Diet, lipids, and antitumor immunity.
Prendeville H, Lynch L. Prendeville H, et al. Cell Mol Immunol. 2022 Mar;19(3):432-444. doi: 10.1038/s41423-021-00781-x. Epub 2022 Jan 5. Cell Mol Immunol. 2022. PMID: 34983949 Free PMC article. Review.
γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.
Kohlgruber AC, Gal-Oz ST, LaMarche NM, Shimazaki M, Duquette D, Koay HF, Nguyen HN, Mina AI, Paras T, Tavakkoli A, von Andrian U, Uldrich AP, Godfrey DI, Banks AS, Shay T, Brenner MB, Lynch L. Kohlgruber AC, et al. Nat Immunol. 2018 May;19(5):464-474. doi: 10.1038/s41590-018-0094-2. Epub 2018 Apr 18. Nat Immunol. 2018. PMID: 29670241 Free PMC article.
17 results