R01 AG015709/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	1
2001	1
2002	1
2005	3
2006	3
2007	2
2008	3
2009	1
2010	1
2011	3
2012	2
2013	4
2014	1
2015	1
2016	3
2017	3
2024	0

1

Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease.

Isaya G. Isaya G. Front Pharmacol. 2014 Mar 3;5:29. doi: 10.3389/fphar.2014.00029. eCollection 2014. Front Pharmacol. 2014. PMID: 24624085 Free PMC article. Review.

2

Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments.

Babady NE, Carelle N, Wells RD, Rouault TA, Hirano M, Lynch DR, Delatycki MB, Wilson RB, Isaya G, Puccio H. Babady NE, et al. Mol Genet Metab. 2007 Sep-Oct;92(1-2):23-35. doi: 10.1016/j.ymgme.2007.05.009. Epub 2007 Jun 26. Mol Genet Metab. 2007. PMID: 17596984 Free PMC article. Review.

3

Iron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia.

Vaubel RA, Isaya G. Vaubel RA, et al. Mol Cell Neurosci. 2013 Jul;55:50-61. doi: 10.1016/j.mcn.2012.08.003. Epub 2012 Aug 11. Mol Cell Neurosci. 2013. PMID: 22917739 Free PMC article. Review.

4

Friedreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency.

Patel PI, Isaya G. Patel PI, et al. Am J Hum Genet. 2001 Jul;69(1):15-24. doi: 10.1086/321283. Epub 2001 Jun 4. Am J Hum Genet. 2001. PMID: 11391483 Free PMC article. Review. No abstract available.

5

Chelatases: distort to select?

Al-Karadaghi S, Franco R, Hansson M, Shelnutt JA, Isaya G, Ferreira GC. Al-Karadaghi S, et al. Trends Biochem Sci. 2006 Mar;31(3):135-42. doi: 10.1016/j.tibs.2006.01.001. Epub 2006 Feb 15. Trends Biochem Sci. 2006. PMID: 16469498 Free PMC article.

6

The Structure of the Complex between Yeast Frataxin and Ferrochelatase: CHARACTERIZATION AND PRE-STEADY STATE REACTION OF FERROUS IRON DELIVERY AND HEME SYNTHESIS.

Söderberg C, Gillam ME, Ahlgren EC, Hunter GA, Gakh O, Isaya G, Ferreira GC, Al-Karadaghi S. Söderberg C, et al. J Biol Chem. 2016 May 27;291(22):11887-98. doi: 10.1074/jbc.M115.701128. Epub 2016 Mar 29. J Biol Chem. 2016. PMID: 27026703 Free PMC article.

7

SAXS and stability studies of iron-induced oligomers of bacterial frataxin CyaY.

Fekry M, Alshokry W, Grela P, Tchórzewski M, Ahlgren EC, Söderberg CA, Gakh O, Isaya G, Al-Karadaghi S. Fekry M, et al. PLoS One. 2017 Sep 20;12(9):e0184961. doi: 10.1371/journal.pone.0184961. eCollection 2017. PLoS One. 2017. PMID: 28931050 Free PMC article.

8

Iron-induced oligomerization of human FXN81-210 and bacterial CyaY frataxin and the effect of iron chelators.

Ahlgren EC, Fekry M, Wiemann M, Söderberg CA, Bernfur K, Gakh O, Rasmussen M, Højrup P, Emanuelsson C, Isaya G, Al-Karadaghi S. Ahlgren EC, et al. PLoS One. 2017 Dec 4;12(12):e0188937. doi: 10.1371/journal.pone.0188937. eCollection 2017. PLoS One. 2017. PMID: 29200434 Free PMC article.

9

PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.

Jobling RK, Assoum M, Gakh O, Blaser S, Raiman JA, Mignot C, Roze E, Dürr A, Brice A, Lévy N, Prasad C, Paton T, Paterson AD, Roslin NM, Marshall CR, Desvignes JP, Roëckel-Trevisiol N, Scherer SW, Rouleau GA, Mégarbané A, Isaya G, Delague V, Yoon G. Jobling RK, et al. Brain. 2015 Jun;138(Pt 6):1505-17. doi: 10.1093/brain/awv057. Epub 2015 Mar 25. Brain. 2015. PMID: 25808372 Free PMC article.

10

Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.

Gakh O, Ranatunga W, Smith DY 4th, Ahlgren EC, Al-Karadaghi S, Thompson JR, Isaya G. Gakh O, et al. J Biol Chem. 2016 Sep 30;291(40):21296-21321. doi: 10.1074/jbc.M116.738542. Epub 2016 Aug 12. J Biol Chem. 2016. PMID: 27519411 Free PMC article.

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