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Page 1
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. Gaul S, et al. J Hepatol. 2021 Jan;74(1):156-167. doi: 10.1016/j.jhep.2020.07.041. Epub 2020 Aug 4. J Hepatol. 2021. PMID: 32763266 Free PMC article.
Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease.
Kanwal F, Shubrook JH, Adams LA, Pfotenhauer K, Wai-Sun Wong V, Wright E, Abdelmalek MF, Harrison SA, Loomba R, Mantzoros CS, Bugianesi E, Eckel RH, Kaplan LM, El-Serag HB, Cusi K. Kanwal F, et al. Gastroenterology. 2021 Nov;161(5):1657-1669. doi: 10.1053/j.gastro.2021.07.049. Epub 2021 Sep 20. Gastroenterology. 2021. PMID: 34602251 Free PMC article. Review.
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis.
Wang S, Li K, Pickholz E, Dobie R, Matchett KP, Henderson NC, Carrico C, Driver I, Borch Jensen M, Chen L, Petitjean M, Bhattacharya D, Fiel MI, Liu X, Kisseleva T, Alon U, Adler M, Medzhitov R, Friedman SL. Wang S, et al. Sci Transl Med. 2023 Jan 4;15(677):eadd3949. doi: 10.1126/scitranslmed.add3949. Epub 2023 Jan 4. Sci Transl Med. 2023. PMID: 36599008 Free PMC article.
Heterogeneity of HSCs in a Mouse Model of NASH.
Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. Rosenthal SB, et al. Hepatology. 2021 Aug;74(2):667-685. doi: 10.1002/hep.31743. Epub 2021 Aug 10. Hepatology. 2021. PMID: 33550587 Free PMC article.
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T. Ma HY, et al. J Hepatol. 2020 May;72(5):946-959. doi: 10.1016/j.jhep.2019.12.016. Epub 2019 Dec 31. J Hepatol. 2020. PMID: 31899206 Free PMC article.
CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.
Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, Hosseini M, Kisseleva T, Brenner DA, Bataller R, Ramachandran P, Karin M, Fu W, Schnabl B. Duan Y, et al. Nat Commun. 2021 Dec 9;12(1):7172. doi: 10.1038/s41467-021-27385-3. Nat Commun. 2021. PMID: 34887405 Free PMC article.
Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution.
Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. Liu X, et al. Gastroenterology. 2020 May;158(6):1728-1744.e14. doi: 10.1053/j.gastro.2020.01.027. Epub 2020 Jan 23. Gastroenterology. 2020. PMID: 31982409 Free PMC article.
The Origin and Fate of Liver Myofibroblasts.
Kim HY, Sakane S, Eguileor A, Carvalho Gontijo Weber R, Lee W, Liu X, Lam K, Ishizuka K, Rosenthal SB, Diggle K, Brenner DA, Kisseleva T. Kim HY, et al. Cell Mol Gastroenterol Hepatol. 2024;17(1):93-106. doi: 10.1016/j.jcmgh.2023.09.008. Epub 2023 Sep 22. Cell Mol Gastroenterol Hepatol. 2024. PMID: 37743012 Free PMC article. Review.
Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease.
Zeng S, Rosati E, Saggau C, Messner B, Chu H, Duan Y, Hartmann P, Wang Y, Ma S, Huang WJM, Lee J, Lee SM, Carvalho-Gontijo R, Zhang V, Hoffmann JP, Kolls JK, Raz E, Brenner DA, Kisseleva T, LeibundGut-Landmann S, Bacher P, Stärkel P, Schnabl B. Zeng S, et al. Cell Host Microbe. 2023 Mar 8;31(3):389-404.e7. doi: 10.1016/j.chom.2023.02.001. Cell Host Microbe. 2023. PMID: 36893735 Free PMC article.
28 results