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Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis.
Elife. 2020 Jul 20;9:e54166. doi: 10.7554/eLife.54166.
Elife. 2020.
PMID: 32686647
Free PMC article.
Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer.
Mah CY, Nguyen ADT, Niijima T, Helm M, Dehairs J, Ryan FJ, Ryan N, Quek LE, Hoy AJ, Don AS, Mills IG, Swinnen JV, Lynn DJ, Nassar ZD, Butler LM.
Mah CY, et al.
Br J Cancer. 2024 Mar;130(5):741-754. doi: 10.1038/s41416-023-02557-8. Epub 2024 Jan 12.
Br J Cancer. 2024.
PMID: 38216720
Free PMC article.
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