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Murine studies and expressional analyses of human cardiac pericytes reveal novel trajectories of SARS-CoV-2 Spike protein-induced microvascular damage.
Avolio E, Srivastava PK, Ji J, Carrabba M, Tsang CTW, Gu Y, Thomas AC, Gupta K, Berger I, Emanueli C, Madeddu P. Avolio E, et al. Signal Transduct Target Ther. 2023 Jun 2;8(1):232. doi: 10.1038/s41392-023-01489-2. Signal Transduct Target Ther. 2023. PMID: 37268620 Free PMC article. No abstract available.
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease.
Avolio E, Carrabba M, Milligan R, Kavanagh Williamson M, Beltrami AP, Gupta K, Elvers KT, Gamez M, Foster RR, Gillespie K, Hamilton F, Arnold D, Berger I, Davidson AD, Hill D, Caputo M, Madeddu P. Avolio E, et al. Clin Sci (Lond). 2021 Dec 22;135(24):2667-2689. doi: 10.1042/CS20210735. Clin Sci (Lond). 2021. PMID: 34807265 Free PMC article.