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Year Number of Results
2017 3
2018 5
2019 7
2020 3
2021 1
2024 0

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14 results

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Page 1
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.
Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King SB, Nikolaev VO, de Wit C, Leichert LI, Feil R, Eaton P, Cuello F. Donzelli S, et al. Sci Rep. 2017 Aug 30;7(1):9938. doi: 10.1038/s41598-017-09275-1. Sci Rep. 2017. PMID: 28855531 Free PMC article.
Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.
Simon JN, Vrellaku B, Monterisi S, Chu SM, Rawlings N, Lomas O, Marchal GA, Waithe D, Syeda F, Gajendragadkar PR, Jayaram R, Sayeed R, Channon KM, Fabritz L, Swietach P, Zaccolo M, Eaton P, Casadei B. Simon JN, et al. Circulation. 2021 Feb 2;143(5):449-465. doi: 10.1161/CIRCULATIONAHA.120.046761. Epub 2020 Nov 13. Circulation. 2021. PMID: 33185461 Free PMC article.
Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension.
Rudyk O, Rowan A, Prysyazhna O, Krasemann S, Hartmann K, Zhang M, Shah AM, Ruppert C, Weiss A, Schermuly RT, Ida T, Akaike T, Zhao L, Eaton P. Rudyk O, et al. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13016-13025. doi: 10.1073/pnas.1904064116. Epub 2019 Jun 11. Proc Natl Acad Sci U S A. 2019. PMID: 31186362 Free PMC article.
PKG1α oxidation negatively regulates food seeking behaviour and reward.
Duraffourd C, Huckstepp RTR, Braren I, Fernandes C, Brock O, Delogu A, Prysyazhna O, Burgoyne J, Eaton P. Duraffourd C, et al. Redox Biol. 2019 Feb;21:101077. doi: 10.1016/j.redox.2018.101077. Epub 2018 Dec 18. Redox Biol. 2019. PMID: 30593979 Free PMC article.
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation.
Stanley CP, Maghzal GJ, Ayer A, Talib J, Giltrap AM, Shengule S, Wolhuter K, Wang Y, Chadha P, Suarna C, Prysyazhna O, Scotcher J, Dunn LL, Prado FM, Nguyen N, Odiba JO, Baell JB, Stasch JP, Yamamoto Y, Di Mascio P, Eaton P, Payne RJ, Stocker R. Stanley CP, et al. Nature. 2019 Feb;566(7745):548-552. doi: 10.1038/s41586-019-0947-3. Epub 2019 Feb 13. Nature. 2019. PMID: 30760924
14 results