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Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo.
Aday S, Hazan-Halevy I, Chamorro-Jorganes A, Anwar M, Goldsmith M, Beazley-Long N, Sahoo S, Dogra N, Sweaad W, Catapano F, Ozaki-Tan S, Angelini GD, Madeddu P, Benest AV, Peer D, Emanueli C. Aday S, et al. Mol Ther. 2021 Jul 7;29(7):2239-2252. doi: 10.1016/j.ymthe.2021.03.015. Epub 2021 Mar 18. Mol Ther. 2021. PMID: 33744469 Free PMC article.
BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase).
Descamps B, Saif J, Benest AV, Biglino G, Bates DO, Chamorro-Jorganes A, Emanueli C. Descamps B, et al. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2117-2125. doi: 10.1161/ATVBAHA.118.311400. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354255 Free article.