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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2012 33
2013 82
2014 96
2015 98
2016 133
2017 167
2018 144
2019 162
2020 145
2021 82
2022 53
2023 49
2024 4

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1,154 results

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Page 1
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Electric-field-stimulated protein mechanics.
Hekstra DR, White KI, Socolich MA, Henning RW, Šrajer V, Ranganathan R. Hekstra DR, et al. Nature. 2016 Dec 15;540(7633):400-405. doi: 10.1038/nature20571. Epub 2016 Dec 7. Nature. 2016. PMID: 27926732 Free PMC article.
Parallel molecular mechanisms for enzyme temperature adaptation.
Pinney MM, Mokhtari DA, Akiva E, Yabukarski F, Sanchez DM, Liang R, Doukov T, Martinez TJ, Babbitt PC, Herschlag D. Pinney MM, et al. Science. 2021 Mar 5;371(6533):eaay2784. doi: 10.1126/science.aay2784. Science. 2021. PMID: 33674467
Ancient plant-like terpene biosynthesis in corals.
Burkhardt I, de Rond T, Chen PY, Moore BS. Burkhardt I, et al. Nat Chem Biol. 2022 Jun;18(6):664-669. doi: 10.1038/s41589-022-01026-2. Epub 2022 May 23. Nat Chem Biol. 2022. PMID: 35606558 Free PMC article.
An ecophysiological explanation for manganese enrichment in rock varnish.
Lingappa UF, Yeager CM, Sharma A, Lanza NL, Morales DP, Xie G, Atencio AD, Chadwick GL, Monteverde DR, Magyar JS, Webb SM, Valentine JS, Hoffman BM, Fischer WW. Lingappa UF, et al. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2025188118. doi: 10.1073/pnas.2025188118. Epub 2021 Jun 14. Proc Natl Acad Sci U S A. 2021. PMID: 34161271 Free PMC article.
Strategies for sample delivery for femtosecond crystallography.
Martiel I, Müller-Werkmeister HM, Cohen AE. Martiel I, et al. Acta Crystallogr D Struct Biol. 2019 Feb 1;75(Pt 2):160-177. doi: 10.1107/S2059798318017953. Epub 2019 Feb 19. Acta Crystallogr D Struct Biol. 2019. PMID: 30821705 Free PMC article. Review.
1,154 results