NS100529/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	2
2016	1
2017	2
2018	2
2019	6
2020	3
2021	7
2022	2
2023	4
2024	4

1

Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.

Bailus BJ, Scheeler SM, Simons J, Sanchez MA, Tshilenge KT, Creus-Muncunill J, Naphade S, Lopez-Ramirez A, Zhang N, Lakshika Madushani K, Moroz S, Loureiro A, Schreiber KH, Hausch F, Kennedy BK, Ehrlich ME, Ellerby LM. Bailus BJ, et al. Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24. Autophagy. 2021. PMID: 34024231 Free PMC article.

2

iPSC-based drug screening for Huntington's disease.

Zhang N, Bailus BJ, Ring KL, Ellerby LM. Zhang N, et al. Brain Res. 2016 May 1;1638(Pt A):42-56. doi: 10.1016/j.brainres.2015.09.020. Epub 2015 Sep 30. Brain Res. 2016. PMID: 26428226 Free PMC article. Review.

3

Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells.

Naphade S, Tshilenge KT, Ellerby LM. Naphade S, et al. Neurotherapeutics. 2019 Oct;16(4):979-998. doi: 10.1007/s13311-019-00810-8. Neurotherapeutics. 2019. PMID: 31792895 Free PMC article. Review.

4

Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.

Tshilenge KT, Aguirre CG, Bons J, Gerencser AA, Basisty N, Song S, Rose J, Lopez-Ramirez A, Naphade S, Loureiro A, Battistoni E, Milani M, Wehrfritz C, Holtz A, Hetz C, Mooney SD, Schilling B, Ellerby LM. Tshilenge KT, et al. Mol Cell Proteomics. 2023 May;22(5):100534. doi: 10.1016/j.mcpro.2023.100534. Epub 2023 Mar 22. Mol Cell Proteomics. 2023. PMID: 36958627 Free PMC article.

5

Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models.

Creus-Muncunill J, Ehrlich ME. Creus-Muncunill J, et al. Neurotherapeutics. 2019 Oct;16(4):957-978. doi: 10.1007/s13311-019-00782-9. Neurotherapeutics. 2019. PMID: 31529216 Free PMC article. Review.

6

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.

Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P, Roussos P, Mooney SD, Ellerby LM, Ehrlich ME. Cirnaru MD, et al. Elife. 2021 Oct 5;10:e65979. doi: 10.7554/eLife.65979. Elife. 2021. PMID: 34609283 Free PMC article.

7

PNA microprobe for label-free detection of expanded trinucleotide repeats.

Asefifeyzabadi N, Durocher G, Tshilenge KT, Alam T, Ellerby LM, Shamsi MH. Asefifeyzabadi N, et al. RSC Adv. 2022 Mar 10;12(13):7757-7761. doi: 10.1039/d2ra00230b. eCollection 2022 Mar 8. RSC Adv. 2022. PMID: 35424746 Free PMC article.

8

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

Cirnaru MD, Creus-Muncunill J, Nelson S, Lewis TB, Watson J, Ellerby LM, Gonzalez-Alegre P, Ehrlich ME. Cirnaru MD, et al. Mov Disord. 2021 Dec;36(12):2780-2794. doi: 10.1002/mds.28750. Epub 2021 Aug 17. Mov Disord. 2021. PMID: 34403156

9

Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.

Song S, Creus Muncunill J, Galicia Aguirre C, Tshilenge KT, Hamilton BW, Gerencser AA, Benlhabib H, Cirnaru MD, Leid M, Mooney SD, Ellerby LM, Ehrlich ME. Song S, et al. Biomedicines. 2022 Sep 23;10(10):2377. doi: 10.3390/biomedicines10102377. Biomedicines. 2022. PMID: 36289639 Free PMC article.

10

Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing.

Tshilenge KT, Bons J, Aguirre CG, Geronimo-Olvera C, Shah S, Rose J, Gerencser AA, Mak SK, Ehrlich ME, Bragg DC, Schilling B, Ellerby LM. Tshilenge KT, et al. Neurobiol Dis. 2024 Jan;190:106367. doi: 10.1016/j.nbd.2023.106367. Epub 2023 Nov 30. Neurobiol Dis. 2024. PMID: 38042508 Free PMC article.

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