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Discovery and validation of a three-gene signature to distinguish COVID-19 and other viral infections in emergency infectious disease presentations: a case-control and observational cohort study.
Li HK, Kaforou M, Rodriguez-Manzano J, Channon-Wells S, Moniri A, Habgood-Coote D, Gupta RK, Mills EA, Arancon D, Lin J, Chiu YH, Pennisi I, Miglietta L, Mehta R, Obaray N, Herberg JA, Wright VJ, Georgiou P, Shallcross LJ, Mentzer AJ, Levin M, Cooke GS, Noursadeghi M, Sriskandan S. Li HK, et al. Lancet Microbe. 2021 Nov;2(11):e594-e603. doi: 10.1016/S2666-5247(21)00145-2. Epub 2021 Aug 16. Lancet Microbe. 2021. PMID: 34423323 Free PMC article.
Mating pair stabilization mediates bacterial conjugation species specificity.
Low WW, Wong JLC, Beltran LC, Seddon C, David S, Kwong HS, Bizeau T, Wang F, Peña A, Costa TRD, Pham B, Chen M, Egelman EH, Beis K, Frankel G. Low WW, et al. Nat Microbiol. 2022 Jul;7(7):1016-1027. doi: 10.1038/s41564-022-01146-4. Epub 2022 Jun 13. Nat Microbiol. 2022. PMID: 35697796 Free PMC article.
Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure.
Wong JLC, David S, Sanchez-Garrido J, Woo JZ, Low WW, Morecchiato F, Giani T, Rossolini GM, Beis K, Brett SJ, Clements A, Aanensen DM, Rouskin S, Frankel G. Wong JLC, et al. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2203593119. doi: 10.1073/pnas.2203593119. Epub 2022 Sep 12. Proc Natl Acad Sci U S A. 2022. PMID: 36095213 Free PMC article.
Antiviral metabolite 3'-deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19.
Mehta R, Chekmeneva E, Jackson H, Sands C, Mills E, Arancon D, Li HK, Arkell P, Rawson TM, Hammond R, Amran M, Haber A, Cooke GS, Noursadeghi M, Kaforou M, Lewis MR, Takats Z, Sriskandan S. Mehta R, et al. Med. 2022 Mar 11;3(3):204-215.e6. doi: 10.1016/j.medj.2022.01.009. Epub 2022 Jan 31. Med. 2022. PMID: 35128501 Free PMC article.