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Page 1
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes.
Nair ATN, Wesolowska-Andersen A, Brorsson C, Rajendrakumar AL, Hapca S, Gan S, Dawed AY, Donnelly LA, McCrimmon R, Doney ASF, Palmer CNA, Mohan V, Anjana RM, Hattersley AT, Dennis JM, Pearson ER. Nair ATN, et al. Nat Med. 2022 May;28(5):982-988. doi: 10.1038/s41591-022-01790-7. Epub 2022 May 9. Nat Med. 2022. PMID: 35534565
Defining drug response for stratified medicine.
Lonergan M, Senn SJ, McNamee C, Daly AK, Sutton R, Hattersley A, Pearson E, Pirmohamed M. Lonergan M, et al. Drug Discov Today. 2017 Jan;22(1):173-179. doi: 10.1016/j.drudis.2016.10.016. Epub 2016 Nov 3. Drug Discov Today. 2017. PMID: 27818254 Review.
Development of a treatment selection algorithm for SGLT2 and DPP-4 inhibitor therapies in people with type 2 diabetes: a retrospective cohort study.
Dennis JM, Young KG, McGovern AP, Mateen BA, Vollmer SJ, Simpson MD, Henley WE, Holman RR, Sattar N, Pearson ER, Hattersley AT, Jones AG, Shields BM; MASTERMIND consortium. Dennis JM, et al. Lancet Digit Health. 2022 Dec;4(12):e873-e883. doi: 10.1016/S2589-7500(22)00174-1. Lancet Digit Health. 2022. PMID: 36427949 Free article.
Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data.
Dennis JM, Henley WE, Weedon MN, Lonergan M, Rodgers LR, Jones AG, Hamilton WT, Sattar N, Janmohamed S, Holman RR, Pearson ER, Shields BM, Hattersley AT; MASTERMIND Consortium. Dennis JM, et al. Diabetes Care. 2018 Sep;41(9):1844-1853. doi: 10.2337/dc18-0344. Epub 2018 Aug 2. Diabetes Care. 2018. PMID: 30072404 Free PMC article.
36 results