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Year Number of Results
2013 6
2014 6
2015 12
2016 8
2017 6
2018 5
2019 8
2020 11
2021 7
2022 6
2023 4
2024 0

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65 results

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Page 1
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
Labiano I, Agirre-Lizaso A, Olaizola P, Echebarria A, Huici-Izagirre M, Olaizola I, Esparza-Baquer A, Sharif O, Hijona E, Milkiewicz P, Milkiewicz M, González-Romero F, Aspichueta P, Monte MJ, Marin JJG, Vucur M, Luedde T, Marzioni M, Mann DA, Bujanda L, Rodrigues PM, Banales JM, Perugorria MJ. Labiano I, et al. J Hepatol. 2022 Oct;77(4):991-1004. doi: 10.1016/j.jhep.2022.05.044. Epub 2022 Jun 22. J Hepatol. 2022. PMID: 35750136 Free article.
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. Malehmir M, et al. Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1. Nat Med. 2019. PMID: 30936549 Free article.
Cellular senescence drives age-dependent hepatic steatosis.
Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. Ogrodnik M, et al. Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691. Nat Commun. 2017. PMID: 28608850 Free PMC article.
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma.
Hall Z, Chiarugi D, Charidemou E, Leslie J, Scott E, Pellegrinet L, Allison M, Mocciaro G, Anstee QM, Evan GI, Hoare M, Vidal-Puig A, Oakley F, Vacca M, Griffin JL. Hall Z, et al. Hepatology. 2021 Mar;73(3):1028-1044. doi: 10.1002/hep.31391. Epub 2020 Nov 3. Hepatology. 2021. PMID: 32460431
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. Esparza-Baquer A, et al. Gut. 2021 Jul;70(7):1345-1361. doi: 10.1136/gutjnl-2019-319227. Epub 2020 Sep 9. Gut. 2021. PMID: 32907830 Free PMC article.
Editorial overview: Fibrosis.
Borthwick L, Oakley F. Borthwick L, et al. Curr Opin Pharmacol. 2019 Dec;49:vi-vii. doi: 10.1016/j.coph.2019.10.003. Epub 2019 Nov 5. Curr Opin Pharmacol. 2019. PMID: 31699602 No abstract available.
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.
Lagnado A, Leslie J, Ruchaud-Sparagano MH, Victorelli S, Hirsova P, Ogrodnik M, Collins AL, Vizioli MG, Habiballa L, Saretzki G, Evans SA, Salmonowicz H, Hruby A, Geh D, Pavelko KD, Dolan D, Reeves HL, Grellscheid S, Wilson CH, Pandanaboyana S, Doolittle M, von Zglinicki T, Oakley F, Gallage S, Wilson CL, Birch J, Carroll B, Chapman J, Heikenwalder M, Neretti N, Khosla S, Masuda CA, Tchkonia T, Kirkland JL, Jurk D, Mann DA, Passos JF. Lagnado A, et al. EMBO J. 2021 May 3;40(9):e106048. doi: 10.15252/embj.2020106048. Epub 2021 Mar 25. EMBO J. 2021. PMID: 33764576 Free PMC article.
Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.
Garcia-Macia M, Santos-Ledo A, Leslie J, Paish HL, Collins AL, Scott RS, Watson A, Burgoyne RA, White S, French J, Hammond J, Borthwick LA, Mann J, Bolaños JP, Korolchuk VI, Oakley F, Mann DA. Garcia-Macia M, et al. Hepatology. 2021 Dec;74(6):3441-3459. doi: 10.1002/hep.32048. Epub 2021 Sep 21. Hepatology. 2021. PMID: 34233024 Free article.
Epigenetic reprogramming in liver fibrosis and cancer.
Wilson CL, Mann DA, Borthwick LA. Wilson CL, et al. Adv Drug Deliv Rev. 2017 Nov 1;121:124-132. doi: 10.1016/j.addr.2017.10.011. Epub 2017 Oct 25. Adv Drug Deliv Rev. 2017. PMID: 29079534 Free PMC article. Review.
65 results