MC_UU_00016/3/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	3
2018	5
2019	5
2020	2
2021	3
2022	1
2023	1
2024	0

1

Alternative Lengthening of Telomeres: Lessons to Be Learned from Telomeric DNA Double-Strand Break Repair.

Kent T, Clynes D. Kent T, et al. Genes (Basel). 2021 Oct 29;12(11):1734. doi: 10.3390/genes12111734. Genes (Basel). 2021. PMID: 34828344 Free PMC article. Review.

2

Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA.

Rose AM, Goncalves T, Cunniffe S, Geiller HEB, Kent T, Shepherd S, Ratnaweera M, O'Sullivan RJ, Gibbons RJ, Clynes D. Rose AM, et al. Nucleic Acids Res. 2023 Jul 21;51(13):6509-6527. doi: 10.1093/nar/gkad150. Nucleic Acids Res. 2023. PMID: 36940725 Free PMC article.

3

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.

Truch J, Downes DJ, Scott C, Gür ER, Telenius JM, Repapi E, Schwessinger R, Gosden M, Brown JM, Taylor S, Cheong PL, Hughes JR, Higgs DR, Gibbons RJ. Truch J, et al. Nat Commun. 2022 Jun 17;13(1):3485. doi: 10.1038/s41467-022-31194-7. Nat Commun. 2022. PMID: 35710802 Free PMC article.

4

Mutant IDH1 Promotes Glioma Formation In Vivo.

Philip B, Yu DX, Silvis MR, Shin CH, Robinson JP, Robinson GL, Welker AE, Angel SN, Tripp SR, Sonnen JA, VanBrocklin MW, Gibbons RJ, Looper RE, Colman H, Holmen SL. Philip B, et al. Cell Rep. 2018 May 1;23(5):1553-1564. doi: 10.1016/j.celrep.2018.03.133. Cell Rep. 2018. PMID: 29719265 Free PMC article.

5

Genetic and functional insights into CDA-I prevalence and pathogenesis.

Olijnik AA, Roy NBA, Scott C, Marsh JA, Brown J, Lauschke K, Ask K, Roberts N, Downes DJ, Brolih S, Johnson E, Xella B, Proven M, Hipkiss R, Ryan K, Frisk P, Mäkk J, Stattin EM, Sadasivam N, McIlwaine L, Hill QA, Renella R, Hughes JR, Gibbons RJ, Groth A, McHugh PJ, Higgs DR, Buckle VJ, Babbs C. Olijnik AA, et al. J Med Genet. 2021 Mar;58(3):185-195. doi: 10.1136/jmedgenet-2020-106880. Epub 2020 Jun 9. J Med Genet. 2021. PMID: 32518175 Free PMC article.

6

How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.

Truch J, Telenius J, Higgs DR, Gibbons RJ. Truch J, et al. Methods Mol Biol. 2018;1832:105-130. doi: 10.1007/978-1-4939-8663-7_6. Methods Mol Biol. 2018. PMID: 30073524

7

ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation.

Marano D, Fioriniello S, Fiorillo F, Gibbons RJ, D'Esposito M, Della Ragione F. Marano D, et al. Int J Mol Sci. 2019 Oct 29;20(21):5371. doi: 10.3390/ijms20215371. Int J Mol Sci. 2019. PMID: 31671722 Free PMC article.

8

A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker.

Bozhilov YK, Downes DJ, Telenius J, Marieke Oudelaar A, Olivier EN, Mountford JC, Hughes JR, Gibbons RJ, Higgs DR. Bozhilov YK, et al. Nat Commun. 2021 Jun 21;12(1):3806. doi: 10.1038/s41467-021-23980-6. Nat Commun. 2021. PMID: 34155213 Free PMC article.

9

The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats.

Nguyen DT, Voon HPJ, Xella B, Scott C, Clynes D, Babbs C, Ayyub H, Kerry J, Sharpe JA, Sloane-Stanley JA, Butler S, Fisher CA, Gray NE, Jenuwein T, Higgs DR, Gibbons RJ. Nguyen DT, et al. EMBO Rep. 2017 Jun;18(6):914-928. doi: 10.15252/embr.201643078. Epub 2017 May 9. EMBO Rep. 2017. PMID: 28487353 Free PMC article.

10

The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.

Young CC, Baker RM, Howlett CJ, Hryciw T, Herman JE, Higgs D, Gibbons R, Crawford H, Brown A, Pin CL. Young CC, et al. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):93-113. doi: 10.1016/j.jcmgh.2018.09.004. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510993 Free PMC article.

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