K22 CA151638/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	2
2011	4
2012	6
2013	2
2014	4
2015	1
2016	1
2020	1
2024	0

1

Ribas A, Lo RS. Ribas A, et al. Cancer Discov. 2020 May;10(5):640-642. doi: 10.1158/2159-8290.CD-20-0231. Cancer Discov. 2020. PMID: 32357967 Free PMC article.

2

Combinatorial therapies to overcome B-RAF inhibitor resistance in melanomas.

Lo RS. Lo RS. Pharmacogenomics. 2012 Jan;13(2):125-8. doi: 10.2217/pgs.11.166. Pharmacogenomics. 2012. PMID: 22256862 Free PMC article. No abstract available.

3

JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma.

Titz B, Lomova A, Le A, Hugo W, Kong X, Ten Hoeve J, Friedman M, Shi H, Moriceau G, Song C, Hong A, Atefi M, Li R, Komisopoulou E, Ribas A, Lo RS, Graeber TG. Titz B, et al. Cell Discov. 2016 Sep 6;2:16028. doi: 10.1038/celldisc.2016.28. eCollection 2016. Cell Discov. 2016. PMID: 27648299 Free PMC article.

4

Combinatorial treatments that overcome PDGFRβ-driven resistance of melanoma cells to V600EB-RAF inhibition.

Shi H, Kong X, Ribas A, Lo RS. Shi H, et al. Cancer Res. 2011 Aug 1;71(15):5067-74. doi: 10.1158/0008-5472.CAN-11-0140. Cancer Res. 2011. PMID: 21803746 Free PMC article.

5

The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.

Paraiso KH, Haarberg HE, Wood E, Rebecca VW, Chen YA, Xiang Y, Ribas A, Lo RS, Weber JS, Sondak VK, John JK, Sarnaik AA, Koomen JM, Smalley KS. Paraiso KH, et al. Clin Cancer Res. 2012 May 1;18(9):2502-14. doi: 10.1158/1078-0432.CCR-11-2612. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351686 Free PMC article.

6

Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis.

Parmenter TJ, Kleinschmidt M, Kinross KM, Bond ST, Li J, Kaadige MR, Rao A, Sheppard KE, Hugo W, Pupo GM, Pearson RB, McGee SL, Long GV, Scolyer RA, Rizos H, Lo RS, Cullinane C, Ayer DE, Ribas A, Johnstone RW, Hicks RJ, McArthur GA. Parmenter TJ, et al. Cancer Discov. 2014 Apr;4(4):423-33. doi: 10.1158/2159-8290.CD-13-0440. Epub 2014 Jan 27. Cancer Discov. 2014. PMID: 24469106 Free PMC article.

7

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations.

Niehr F, von Euw E, Attar N, Guo D, Matsunaga D, Sazegar H, Ng C, Glaspy JA, Recio JA, Lo RS, Mischel PS, Comin-Anduix B, Ribas A. Niehr F, et al. J Transl Med. 2011 May 24;9:76. doi: 10.1186/1479-5876-9-76. J Transl Med. 2011. PMID: 21609436 Free PMC article.

8

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.

Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H, Chen Z, Lee MK, Attar N, Sazegar H, Chodon T, Nelson SF, McArthur G, Sosman JA, Ribas A, Lo RS. Nazarian R, et al. Nature. 2010 Dec 16;468(7326):973-7. doi: 10.1038/nature09626. Epub 2010 Nov 24. Nature. 2010. PMID: 21107323 Free PMC article.

9

Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.

Shi H, Moriceau G, Kong X, Lee MK, Lee H, Koya RC, Ng C, Chodon T, Scolyer RA, Dahlman KB, Sosman JA, Kefford RF, Long GV, Nelson SF, Ribas A, Lo RS. Shi H, et al. Nat Commun. 2012 Mar 6;3:724. doi: 10.1038/ncomms1727. Nat Commun. 2012. PMID: 22395615 Free PMC article.

10

Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.

Søndergaard JN, Nazarian R, Wang Q, Guo D, Hsueh T, Mok S, Sazegar H, MacConaill LE, Barretina JG, Kehoe SM, Attar N, von Euw E, Zuckerman JE, Chmielowski B, Comin-Anduix B, Koya RC, Mischel PS, Lo RS, Ribas A. Søndergaard JN, et al. J Transl Med. 2010 Apr 20;8:39. doi: 10.1186/1479-5876-8-39. J Transl Med. 2010. PMID: 20406486 Free PMC article.

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