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Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma.
Mascharak S, Guo JL, Foster DS, Khan A, Davitt MF, Nguyen AT, Burcham AR, Chinta MS, Guardino NJ, Griffin M, Lopez DM, Miller E, Januszyk M, Raghavan SS, Longacre TA, Delitto DJ, Norton JA, Longaker MT. Mascharak S, et al. Cell Rep Med. 2023 Nov 21;4(11):101248. doi: 10.1016/j.xcrm.2023.101248. Epub 2023 Oct 20. Cell Rep Med. 2023. PMID: 37865092 Free PMC article.
Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells.
Padmanabhan J, Chen K, Sivaraj D, Henn D, Kuehlmann BA, Kussie HC, Zhao ET, Kahn A, Bonham CA, Dohi T, Beck TC, Trotsyuk AA, Stern-Buchbinder ZA, Than PA, Hosseini HS, Barrera JA, Magbual NJ, Leeolou MC, Fischer KS, Tigchelaar SS, Lin JQ, Perrault DP, Borrelli MR, Kwon SH, Maan ZN, Dunn JCY, Nazerali R, Januszyk M, Prantl L, Gurtner GC. Padmanabhan J, et al. Nat Biomed Eng. 2023 Nov;7(11):1419-1436. doi: 10.1038/s41551-023-01091-5. Epub 2023 Sep 25. Nat Biomed Eng. 2023. PMID: 37749310 Free PMC article.