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Year | Number of Results |
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2015 | 1 |
2016 | 1 |
2017 | 1 |
2018 | 2 |
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2024 | 0 |
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Syntheses of Human TLR8-Specific Small-Molecule Agonists.
Methods Mol Biol. 2017;1494:29-44. doi: 10.1007/978-1-4939-6445-1_3.
Methods Mol Biol. 2017.
PMID: 27718184
High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens.
Counoupas C, Pino P, Stella AO, Ashley C, Lukeman H, Bhattacharyya ND, Tada T, Anchisi S, Metayer C, Martinis J, Aggarwal A, Dcosta BM, Britton WJ, Kint J, Wurm MJ, Landau NR, Steain M, Turville SG, Wurm FM, David SA, Triccas JA.
Counoupas C, et al.
Microbiol Spectr. 2022 Feb 23;10(1):e0169521. doi: 10.1128/spectrum.01695-21. Epub 2022 Feb 16.
Microbiol Spectr. 2022.
PMID: 35171046
Free PMC article.
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Human Toll-like Receptor (TLR) 8-Specific Agonistic Activity in Substituted Pyrimidine-2,4-diamines.
Beesu M, Salyer AC, Trautman KL, Hill JK, David SA.
Beesu M, et al.
J Med Chem. 2016 Sep 8;59(17):8082-93. doi: 10.1021/acs.jmedchem.6b00872. Epub 2016 Aug 19.
J Med Chem. 2016.
PMID: 27513008
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Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue.
Yoo E, Salyer ACD, Brush MJH, Li Y, Trautman KL, Shukla NM, De Beuckelaer A, Lienenklaus S, Deswarte K, Lambrecht BN, De Geest BG, David SA.
Yoo E, et al.
Bioconjug Chem. 2018 Aug 15;29(8):2741-2754. doi: 10.1021/acs.bioconjchem.8b00386. Epub 2018 Jul 17.
Bioconjug Chem. 2018.
PMID: 29969553
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Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.
Nuhn L, Van Hoecke L, Deswarte K, Schepens B, Li Y, Lambrecht BN, De Koker S, David SA, Saelens X, De Geest BG.
Nuhn L, et al.
Biomaterials. 2018 Sep;178:643-651. doi: 10.1016/j.biomaterials.2018.03.026. Epub 2018 Mar 16.
Biomaterials. 2018.
PMID: 29573820
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Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
Beesu M, Caruso G, Salyer AC, Khetani KK, Sil D, Weerasinghe M, Tanji H, Ohto U, Shimizu T, David SA.
Beesu M, et al.
J Med Chem. 2015 Oct 8;58(19):7833-49. doi: 10.1021/acs.jmedchem.5b01087. Epub 2015 Sep 22.
J Med Chem. 2015.
PMID: 26351878
Free PMC article.
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