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A Native Mass Spectrometry-Based Assay for Rapid Assessment of the Empty:Full Capsid Ratio in Adeno-Associated Virus Gene Therapy Products.
Anal Chem. 2021 Sep 28;93(38):12817-12821. doi: 10.1021/acs.analchem.1c02828. Epub 2021 Sep 14.
Anal Chem. 2021.
PMID: 34519199
Free PMC article.
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency.
Guapo F, Donohue N, Strasser L, Boi S, Füssl F, Rainbow-Fletcher A, Getty P, Anderson I, Barron N, Bones J.
Guapo F, et al.
Int J Mol Sci. 2024 Feb 28;25(5):2785. doi: 10.3390/ijms25052785.
Int J Mol Sci. 2024.
PMID: 38474031
Free PMC article.
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