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Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI.
Nat Struct Mol Biol. 2011 May;18(5):571-6. doi: 10.1038/nsmb.2044. Epub 2011 Apr 24.
Nat Struct Mol Biol. 2011.
PMID: 21516097
Free PMC article.
A fluorescent biosensor reveals conformational changes in human immunoglobulin E Fc: implications for mechanisms of receptor binding, inhibition, and allergen recognition.
Hunt J, Keeble AH, Dale RE, Corbett MK, Beavil RL, Levitt J, Swann MJ, Suhling K, Ameer-Beg S, Sutton BJ, Beavil AJ.
Hunt J, et al.
J Biol Chem. 2012 May 18;287(21):17459-17470. doi: 10.1074/jbc.M111.331967. Epub 2012 Mar 22.
J Biol Chem. 2012.
PMID: 22442150
Free PMC article.
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