First insights for targeted therapies in odontogenic myxoma.
Pereira NB, Bastos VC, de Souza JC, Diniz MG, Vitório JG, Kitten GT, de Oliveira Andrade L, de Avelar GF, Castro WH, Bernardes VF, Dias AAM, Gomez RS, Gomes CC.
Pereira NB, et al.
Clin Oral Investig. 2020 Jul;24(7):2451-2458. doi: 10.1007/s00784-019-03107-4. Epub 2019 Nov 12.
Clin Oral Investig. 2020.
PMID: 31713744
CONCLUSIONS: The MAPK pathway is activated in OM and its inhibition leads to tumor shrinkage in PDX and cell culture models. CLINICAL RELEVANCE: Our results offer a pre-clinical frame for OM-targeted therapy. Further work is needed to determine if this initial findi …
CONCLUSIONS: The MAPK pathway is activated in OM and its inhibition leads to tumor shrinkage in PDX and cell culture models. CLINICAL …