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Oxidized Substrates of APEH as a Tool to Study the Endoprotease Activity of the Enzyme.
Int J Mol Sci. 2021 Dec 31;23(1):443. doi: 10.3390/ijms23010443.
Int J Mol Sci. 2021.
PMID: 35008880
Free PMC article.
Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions.
Smaldone G, Caruso D, Sandomenico A, Iaccarino E, Focà A, Ruggiero A, Ruvo M, Vitagliano L.
Smaldone G, et al.
Int J Mol Sci. 2021 Oct 2;22(19):10700. doi: 10.3390/ijms221910700.
Int J Mol Sci. 2021.
PMID: 34639041
Free PMC article.
Surprisingly, GADD45alpha and GADD45beta, when heated, form high-molecular weight species that exhibit features (ThT binding and intrinsic label-free UV/visible fluorescence) proper of amyloid-like aggregates. Cell viability studies demonstrate that they are endowed with a …
Surprisingly, GADD45alpha and GADD45beta, when heated, form high-molecular weight species that exhibit features (ThT binding and intrinsic l …
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Development of a New Highly Selective Monoclonal Antibody against Preferentially Expressed Antigen in Melanoma (PRAME) and Identification of the Target Epitope by Bio-Layer Interferometry.
Sivaccumar JP, Leonardi A, Iaccarino E, Corvino G, Sanguigno L, Chambery A, Russo R, Valletta M, Latino D, Capasso D, Doti N, Ruvo M, Sandomenico A.
Sivaccumar JP, et al.
Int J Mol Sci. 2021 Mar 20;22(6):3166. doi: 10.3390/ijms22063166.
Int J Mol Sci. 2021.
PMID: 33804612
Free PMC article.
BACKGROUND: Monoclonal antibodies (mAbs) against cancer biomarkers are key reagents in diagnosis and therapy. One such relevant biomarker is a preferentially expressed antigen in melanoma (PRAME) that is selectively expressed in many tumors. ...
BACKGROUND: Monoclonal antibodies (mAbs) against cancer biomarkers are key reagents in diagnosis and therapy. One such relevant bioma …
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Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation.
Di Micco S, Musella S, Sala M, Scala MC, Andrei G, Snoeck R, Bifulco G, Campiglia P, Fasano A.
Di Micco S, et al.
Int J Mol Sci. 2021 Aug 30;22(17):9427. doi: 10.3390/ijms22179427.
Int J Mol Sci. 2021.
PMID: 34502335
Free PMC article.
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