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PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.
Nat Chem Biol. 2022 Aug;18(8):821-830. doi: 10.1038/s41589-022-01024-4. Epub 2022 May 16.
Nat Chem Biol. 2022.
PMID: 35578032
Free PMC article.
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation.
Fraser BJ, Beldar S, Seitova A, Hutchinson A, Mannar D, Li Y, Kwon D, Tan R, Wilson RP, Leopold K, Subramaniam S, Halabelian L, Arrowsmith CH, Bénard F.
Fraser BJ, et al.
Nat Chem Biol. 2022 Sep;18(9):963-971. doi: 10.1038/s41589-022-01059-7. Epub 2022 Jun 8.
Nat Chem Biol. 2022.
PMID: 35676539
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The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Wei Y, Redel C, Ahlner A, Lemak A, Johansson-Åkhe I, Houliston S, Kenney TMG, Tamachi A, Morad V, Duan S, Andrews DW, Wallner B, Sunnerhagen M, Arrowsmith CH, Penn LZ.
Wei Y, et al.
Nucleic Acids Res. 2022 Apr 8;50(6):3505-3522. doi: 10.1093/nar/gkac138.
Nucleic Acids Res. 2022.
PMID: 35244724
Free PMC article.
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