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LC-FACSeq is a method for detecting rare clones in leukemia.
Hu EY, Blachly JS, Saygin C, Ozer HG, Workman SE, Lozanski A, Doong TJ, Chiang CL, Bhat S, Rogers KA, Woyach JA, Coombes KR, Jones D, Muthusamy N, Lozanski G, Byrd JC. Hu EY, et al. JCI Insight. 2020 Jun 18;5(12):e134973. doi: 10.1172/jci.insight.134973. JCI Insight. 2020. PMID: 32554930 Free PMC article.
The ROR1 antibody-drug conjugate huXBR1-402-G5-PNU effectively targets ROR1+ leukemia.
Hu EY, Do P, Goswami S, Nunes J, Chiang CL, Elgamal S, Ventura AM, Cheney C, Zapolnik K, Williams E, Mani R, Frissora F, Mo X, Waldmeier L, Beerli RR, Peng H, Rader C, Long M, Grawunder U, Byrd JC, Muthusamy N. Hu EY, et al. Blood Adv. 2021 Aug 24;5(16):3152-3162. doi: 10.1182/bloodadvances.2020003276. Blood Adv. 2021. PMID: 34424320 Free PMC article.
CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq.
Walker LA, Sovic MG, Chiang CL, Hu E, Denninger JK, Chen X, Kirby ED, Byrd JC, Muthusamy N, Bundschuh R, Yan P. Walker LA, et al. J Transl Med. 2020 Feb 10;18(1):63. doi: 10.1186/s12967-020-02247-6. J Transl Med. 2020. PMID: 32039730 Free PMC article.
Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq.
Saygin C, Hu E, Zhang P, Sher S, Lozanski A, Doong TJ, Nicolet D, Orwick S, Labanowska J, Skinner JN, Cempre C, Kauffman T, Goettl VM, Heerema NA, Abruzzo L, Miller C, Lapalombella R, Behbehani G, Mims AS, Larkin K, Grieselhuber N, Walker A, Bhatnagar B, Bloomfield CD, Byrd JC, Lozanski G, Blachly JS. Saygin C, et al. Leukemia. 2021 Dec;35(12):3406-3420. doi: 10.1038/s41375-021-01295-1. Epub 2021 May 21. Leukemia. 2021. PMID: 34021247 Free PMC article.