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Page 1
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, Henry JY, Spain L, Ben Aissa A, Georgiou A, Wong YNS, Smith M, Strauss D, Hayes A, Nicol D, O'Brien T, Mårtensson L, Ljungars A, Teige I, Frendéus B; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia; Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA. Arce Vargas F, et al. Cancer Cell. 2018 Apr 9;33(4):649-663.e4. doi: 10.1016/j.ccell.2018.02.010. Epub 2018 Mar 22. Cancer Cell. 2018. PMID: 29576375 Free PMC article.
A KRAS-responsive long non-coding RNA controls microRNA processing.
Shi L, Magee P, Fassan M, Sahoo S, Leong HS, Lee D, Sellers R, Brullé-Soumaré L, Cairo S, Monteverde T, Volinia S, Smith DD, Di Leva G, Galuppini F, Paliouras AR, Zeng K, O'Keefe R, Garofalo M. Shi L, et al. Nat Commun. 2021 Apr 1;12(1):2038. doi: 10.1038/s41467-021-22337-3. Nat Commun. 2021. PMID: 33795683 Free PMC article.
KRAS induces lung tumorigenesis through microRNAs modulation.
Shi L, Middleton J, Jeon YJ, Magee P, Veneziano D, Laganà A, Leong HS, Sahoo S, Fassan M, Booton R, Shah R, Crosbie PAJ, Garofalo M. Shi L, et al. Cell Death Dis. 2018 Feb 13;9(2):219. doi: 10.1038/s41419-017-0243-9. Cell Death Dis. 2018. PMID: 29440633 Free PMC article.
Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients.
Geary B, Walker MJ, Snow JT, Lee DCH, Pernemalm M, Maleki-Dizaji S, Azadbakht N, Apostolidou S, Barnes J, Krysiak P, Shah R, Booton R, Dive C, Crosbie PA, Whetton AD. Geary B, et al. J Proteome Res. 2019 Sep 6;18(9):3369-3382. doi: 10.1021/acs.jproteome.9b00287. Epub 2019 Aug 21. J Proteome Res. 2019. PMID: 31408348
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Arce Vargas F, Furness AJS, Solomon I, Joshi K, Mekkaoui L, Lesko MH, Miranda Rota E, Dahan R, Georgiou A, Sledzinska A, Ben Aissa A, Franz D, Werner Sunderland M, Wong YNS, Henry JY, O'Brien T, Nicol D, Challacombe B, Beers SA; Melanoma TRACERx Consortium; Renal TRACERx Consortium; Lung TRACERx Consortium; Turajlic S, Gore M, Larkin J, Swanton C, Chester KA, Pule M, Ravetch JV, Marafioti T, Peggs KS, Quezada SA. Arce Vargas F, et al. Immunity. 2017 Apr 18;46(4):577-586. doi: 10.1016/j.immuni.2017.03.013. Epub 2017 Apr 11. Immunity. 2017. PMID: 28410988 Free PMC article.