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Page 1
Recent Progress in Histone Demethylase Inhibitors.
McAllister TE, England KS, Hopkinson RJ, Brennan PE, Kawamura A, Schofield CJ. McAllister TE, et al. J Med Chem. 2016 Feb 25;59(4):1308-29. doi: 10.1021/acs.jmedchem.5b01758. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26710088 Review.
Structural studies on human 2-oxoglutarate dependent oxygenases.
McDonough MA, Loenarz C, Chowdhury R, Clifton IJ, Schofield CJ. McDonough MA, et al. Curr Opin Struct Biol. 2010 Dec;20(6):659-72. doi: 10.1016/j.sbi.2010.08.006. Epub 2010 Sep 29. Curr Opin Struct Biol. 2010. PMID: 20888218 Review.
Inhibition of 2-oxoglutarate dependent oxygenases.
Rose NR, McDonough MA, King ON, Kawamura A, Schofield CJ. Rose NR, et al. Chem Soc Rev. 2011 Aug;40(8):4364-97. doi: 10.1039/c0cs00203h. Epub 2011 Mar 10. Chem Soc Rev. 2011. PMID: 21390379 Review.
Targeting Protein-Protein Interactions in the HIF System.
Wilkins SE, Abboud MI, Hancock RL, Schofield CJ. Wilkins SE, et al. ChemMedChem. 2016 Apr 19;11(8):773-86. doi: 10.1002/cmdc.201600012. Epub 2016 Mar 21. ChemMedChem. 2016. PMID: 26997519 Free PMC article. Review.
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.
Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Leśniak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ. Markolovic S, et al. Nat Chem Biol. 2018 Jul;14(7):688-695. doi: 10.1038/s41589-018-0071-y. Epub 2018 Jun 18. Nat Chem Biol. 2018. PMID: 29915238 Free PMC article.
26 results