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Discovery of Palbociclib as a potent c-Myc G4 stabilizer for lung cancer treatment using molecular docking, molecular dynamics simulation, and in vitro activity evaluation.
Gao J, Liang C, Yin J, Bai Y, Hu D. Gao J, et al. Mol Divers. 2024 Jan 22. doi: 10.1007/s11030-023-10789-2. Online ahead of print. Mol Divers. 2024. PMID: 38246949
These results suggest that Palbociclib holds promise as a novel c-Myc G4 stabilizer for treating cancers associated with abnormal c-Myc activity; further optimization and development are warranted....
These results suggest that Palbociclib holds promise as a novel c-Myc G4 stabilizer for treating cancers associated with abnormal c-Myc acti …