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The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1.
J Biol Chem. 2005 Aug 12;280(32):29047-52. doi: 10.1074/jbc.M503166200. Epub 2005 Jun 20.
J Biol Chem. 2005.
PMID: 15970587
Free article.
Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation.
Song Y, Chan JM, Tovian Z, Secrest A, Nagy E, Krysiak K, Bergan K, Parniak MA, Oldfield E.
Song Y, et al.
Bioorg Med Chem. 2008 Oct 1;16(19):8959-67. doi: 10.1016/j.bmc.2008.08.047. Epub 2008 Aug 27.
Bioorg Med Chem. 2008.
PMID: 18789701
Free PMC article.
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