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Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors.
ChemMedChem. 2021 Nov 5;16(21):3360-3367. doi: 10.1002/cmdc.202100392. Epub 2021 Oct 12.
ChemMedChem. 2021.
PMID: 34459148
Free PMC article.
Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.
Strauss J, Wilkinson C, Vidilaseris K, de Castro Ribeiro OM, Liu J, Hillier J, Wichert M, Malinen AM, Gehl B, Jeuken LJ, Pearson AR, Goldman A.
Strauss J, et al.
EMBO Rep. 2024 Feb;25(2):853-875. doi: 10.1038/s44319-023-00037-x. Epub 2024 Jan 5.
EMBO Rep. 2024.
PMID: 38182815
Free PMC article.
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