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Redirect Tropism of Fowl Adenovirus 4 Vector by Modifying Fiber2 with Variable Domain of Heavy-Chain Antibody.
Wang Y, Zou X, Guo X, Zhang Z, Wang M, Hung T, Lu Z. Wang Y, et al. Genes (Basel). 2024 Apr 8;15(4):467. doi: 10.3390/genes15040467. Genes (Basel). 2024. PMID: 38674401 Free PMC article.
Foldon from phage T4 fibritin, a trigger for trimerization, was employed to bridge the tail/shaft domain of fiber2 and VHHs against human CD16A, a key membrane marker of natural killer (NK) cells. Through one step of restriction-assembly, the modified fiber2 was transferre …
Foldon from phage T4 fibritin, a trigger for trimerization, was employed to bridge the tail/shaft domain of fiber2 and VHHs against human CD …