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Dysregulation of TCONS_00006091 contributes to the elevated risk of oral squamous cell carcinoma by upregulating SNAI1, IRS and HMGA2.
Ma D, Chen J, Shi Y, Gao H, Wei Z, Fan J, Wang L. Ma D, et al. Sci Rep. 2024 Apr 26;14(1):9616. doi: 10.1038/s41598-024-60310-4. Sci Rep. 2024. PMID: 38671227 Free PMC article.
The elevated TCONS_00006091 suppressed the expressions of miR-153, miR-370 and let-7g, leading to the increased expression of SNAI1, IRS and HMGA2. Also, promoted cell proliferation and suppressed apoptosis were observed upon the over-expression of TCONS_00006091. ...
The elevated TCONS_00006091 suppressed the expressions of miR-153, miR-370 and let-7g, leading to the increased expression of SNAI1, …