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3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties.
Mariano LNB, Boeing T, Filho VC, Niero R, da Silva LM, de Souza P. Mariano LNB, et al. J Pharm Pharmacol. 2024 Jan 27;76(2):106-114. doi: 10.1093/jpp/rgad123. J Pharm Pharmacol. 2024. PMID: 38166170
CONCLUSION: Together, this study displayed the prolonged diuretic action of DGP and its natriuretic, Ca2+-sparing, and antiurolytic effects. The antioxidative and anti-inflammatory effects of DGP were evidenced in SHR kidneys, opening perspectives for further studie …
CONCLUSION: Together, this study displayed the prolonged diuretic action of DGP and its natriuretic, Ca2+-sparing, and antiurolytic effec
Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu, in Hypertensive Rats.
Mariano LNB, da Silva RCV, Niero R, Cechinel Filho V, da Silva-Santos JE, de Souza P. Mariano LNB, et al. Plants (Basel). 2024 Feb 15;13(4):528. doi: 10.3390/plants13040528. Plants (Basel). 2024. PMID: 38498544 Free PMC article.
The present study expands its actions on the cardiovascular system by evaluating its vasorelaxant and blood pressure-lowering effects in spontaneously hypertensive rats (SHRs). Aortic endothelium-intact (E+) preparations of SHRs pre-contracted by phenylephrine and exposed …
The present study expands its actions on the cardiovascular system by evaluating its vasorelaxant and blood pressure-lowering effects