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Optimization and compartmentalization of a cell-free mixture of DNA amplification and protein translation.
Han F, Xu B, Lu N, Caliari A, Lu H, Xia Y, Su'etsugu M, Xu J, Yomo T. Han F, et al. Appl Microbiol Biotechnol. 2022 Dec;106(24):8139-8149. doi: 10.1007/s00253-022-12278-2. Epub 2022 Nov 10. Appl Microbiol Biotechnol. 2022. PMID: 36355086
Our findings can help to better fine-tune the reaction conditions of RCR-PURE systems and provide new avenues for rewiring the central dogma of molecular biology as self-sustaining systems in synthetic cell models. KEY POINTS: Commercial reconstituted DNA amplification (RC …
Our findings can help to better fine-tune the reaction conditions of RCR-PURE systems and provide new avenues for rewiring the central dogma …
Dynamic Polymer Amphiphiles for Efficient Intracellular and In Vivo Protein Delivery.
Xu J, Li Z, Fan Q, Lv J, Li Y, Cheng Y. Xu J, et al. Adv Mater. 2021 Dec;33(52):e2104355. doi: 10.1002/adma.202104355. Epub 2021 Oct 17. Adv Mater. 2021. PMID: 34658077
The lead supra-amphiphiles screened in the library demonstrate high efficiency in the delivery of various proteins including bovine serum albumin, beta-galactosidase, alpha-chymotrypsin, saporin, R-phycoerythrin, ovalbumin, catalase, and superoxide dismutase, and show grea …
The lead supra-amphiphiles screened in the library demonstrate high efficiency in the delivery of various proteins including bovine serum al …
HbA1c is a predictive factor of severe coronary stenosis and major adverse cardiovascular events in patients with both type 2 diabetes and coronary heart disease.
Jiao X, Zhang Q, Peng P, Shen Y. Jiao X, et al. Diabetol Metab Syndr. 2023 Mar 20;15(1):50. doi: 10.1186/s13098-023-01015-y. Diabetol Metab Syndr. 2023. PMID: 36935502 Free PMC article.
RESULTS: b-HbA1c was positively correlated with the severity of CHD (r = 0.207, p = 0.001), and patients with b-HbA1c > 9% were more likely to have severe CHD. ...
RESULTS: b-HbA1c was positively correlated with the severity of CHD (r = 0.207, p = 0.001), and patients with b-HbA1c > 9% were mo …