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Simultaneous or Prior Activation of Intrahepatic Type I Interferon Signaling Leads to Hepatitis B Virus Persistence in a Mouse Model.
Zou S, Du Y, Huang S, Chen M, Yang X, Li S, Chen Y, Han M, Li J, Yu Q, Littwitz-Salomon E, Huang H, Trilling M, Liu S, Pei R, Liu J, Wang B, Zheng X, Lu M, Dittmer U, Sun S, Yang D, Wu J. Zou S, et al. J Virol. 2021 Nov 23;95(24):e0003421. doi: 10.1128/JVI.00034-21. Epub 2021 Sep 22. J Virol. 2021. PMID: 34550772 Free PMC article.
Lost Small Envelope Protein Expression from Naturally Occurring PreS1 Deletion Mutants of Hepatitis B Virus Is Often Accompanied by Increased HBx and Core Protein Expression as Well as Genome Replication.
Fu S, Zhang J, Yuan Q, Wang Q, Deng Q, Li J, Xia N, Wang Y, Wen Y, Tong S. Fu S, et al. J Virol. 2021 Jun 24;95(14):e0066021. doi: 10.1128/JVI.00660-21. Epub 2021 Jun 24. J Virol. 2021. PMID: 33910956 Free PMC article.
The large (L) and small (S) envelope proteins are translated from the 2.4-kb and 2.1-kb RNAs, respectively, with the majority of the S protein being secreted as noninfectious subviral particles and detected as hepatitis B surface antigen (HBsAg). pgRNA transcription could …
The large (L) and small (S) envelope proteins are translated from the 2.4-kb and 2.1-kb RNAs, respectively, with the majority of the …
A photocontrolled one-pot isothermal amplification and CRISPR-Cas12a assay for rapid detection of SARS-CoV-2 Omicron variants.
Sun Q, Lin H, Li Y, Yuan L, Li B, Ma Y, Wang H, Deng X, Chen H, Tang S. Sun Q, et al. Microbiol Spectr. 2024 Mar 5;12(3):e0364523. doi: 10.1128/spectrum.03645-23. Epub 2024 Feb 6. Microbiol Spectr. 2024. PMID: 38319081 Free PMC article.
CRISPR-Cas technology has widely been applied to detect single-nucleotide mutation and is considered as the next generation of molecular diagnostics. We previously reported the combination of nucleic acid amplification (NAA) and CRISPR-Cas12a system to distinguish major
CRISPR-Cas technology has widely been applied to detect single-nucleotide mutation and is considered as the next generation of molecu …