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2022 8
2023 2
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New insights into activation and function of the AMPK.
Steinberg GR, Hardie DG. Steinberg GR, et al. Nat Rev Mol Cell Biol. 2023 Apr;24(4):255-272. doi: 10.1038/s41580-022-00547-x. Epub 2022 Oct 31. Nat Rev Mol Cell Biol. 2023. PMID: 36316383 Review.
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.
Morrow MR, Batchuluun B, Wu J, Ahmadi E, Leroux JM, Mohammadi-Shemirani P, Desjardins EM, Wang Z, Tsakiridis EE, Lavoie DCT, Reihani A, Smith BK, Kwiecien JM, Lally JSV, Nero TL, Parker MW, Ask K, Scott JW, Jiang L, Paré G, Pinkosky SL, Steinberg GR. Morrow MR, et al. Cell Metab. 2022 Jun 7;34(6):919-936.e8. doi: 10.1016/j.cmet.2022.05.004. Cell Metab. 2022. PMID: 35675800 Free article.
Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice.
Desjardins EM, Wu J, Lavoie DCT, Ahmadi E, Townsend LK, Morrow MR, Wang D, Tsakiridis EE, Batchuluun B, Fayyazi R, Kwiecien JM, Tsakiridis T, Lally JSV, Paré G, Pinkosky SL, Steinberg GR. Desjardins EM, et al. Cell Rep Med. 2023 Sep 19;4(9):101193. doi: 10.1016/j.xcrm.2023.101193. Cell Rep Med. 2023. PMID: 37729871 Free PMC article.
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.
Rhein P, Desjardins EM, Rong P, Ahwazi D, Bonhoure N, Stolte J, Santos MD, Ovens AJ, Ehrlich AM, Sanchez Garcia JL, Ouyang Q, Yabut JM, Kjolby M, Membrez M, Jessen N, Oakhill JS, Treebak JT, Maire P, Scott JW, Sanders MJ, Descombes P, Chen S, Steinberg GR, Sakamoto K. Rhein P, et al. Mol Metab. 2021 Sep;51:101228. doi: 10.1016/j.molmet.2021.101228. Epub 2021 Mar 30. Mol Metab. 2021. PMID: 33798773 Free PMC article.
Metformin-induced reductions in tumor growth involves modulation of the gut microbiome.
Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J, Wu J, Syed S, Lally JSV, Raphenya AR, Blouin MJ, Pollak M, Sacconi A, Blandino G, McArthur AG, Schertzer JD, Surette MG, Collins SM, Bramson JL, Muti P, Tsakiridis T, Steinberg GR. Broadfield LA, et al. Mol Metab. 2022 Jul;61:101498. doi: 10.1016/j.molmet.2022.101498. Epub 2022 Apr 20. Mol Metab. 2022. PMID: 35452877 Free PMC article.
16 results