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miR-155 and miR-146a collectively regulate meningitic Escherichia coli infection-mediated neuroinflammatory responses.
Yang B, Yang R, Xu B, Fu J, Qu X, Li L, Dai M, Tan C, Chen H, Wang X. Yang B, et al. J Neuroinflammation. 2021 May 13;18(1):114. doi: 10.1186/s12974-021-02165-4. J Neuroinflammation. 2021. PMID: 33985523 Free PMC article.
Our previous study showed that E. coli can colonize the brain and cause neuroinflammation. Increasing evidence supports the involvement of miRNAs as key regulators of neuroinflammation. However, it is not clear whether these molecules participate in the regulation of menin …
Our previous study showed that E. coli can colonize the brain and cause neuroinflammation. Increasing evidence supports the involvement of m …
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Yang RC, Qu XY, Xiao SY, Li L, Xu BJ, Fu JY, Lv YJ, Amjad N, Tan C, Kim KS, Chen HC, Wang XR. Yang RC, et al. J Neuroinflammation. 2019 May 15;16(1):101. doi: 10.1186/s12974-019-1497-1. J Neuroinflammation. 2019. PMID: 31092253 Free PMC article.
BACKGROUND: Blood-brain barrier (BBB) disruption and neuroinflammation are considered key mechanisms of pathogenic Escherichia coli invasion of the brain. ...
BACKGROUND: Blood-brain barrier (BBB) disruption and neuroinflammation are considered key mechanisms of pathogenic Escherichia coli i …
Decrease of miR-19b-3p in Brain Microvascular Endothelial Cells Attenuates Meningitic Escherichia coli-Induced Neuroinflammation via TNFAIP3-Mediated NF-κB Inhibition.
Amjad N, Yang R, Li L, Fu J, Yang B, Xu B, Tan C, Chen H, Wang X. Amjad N, et al. Pathogens. 2019 Nov 27;8(4):268. doi: 10.3390/pathogens8040268. Pathogens. 2019. PMID: 31783671 Free PMC article.
During this process, the host needs to reasonably balance the battle between bacteria and brain microvascular endothelial cells (BMECs) to minimize inflammatory damage, but this quenching of neuroinflammatory responses at the BBB is unclear. MicroRNAs (miRNAs) are widely recogniz …
During this process, the host needs to reasonably balance the battle between bacteria and brain microvascular endothelial cells (BMECs) to m …
ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells.
Tan Z, Zhang W, Sun J, Fu Z, Ke X, Zheng C, Zhang Y, Li P, Liu Y, Hu Q, Wang H, Zheng Z. Tan Z, et al. J Neuroinflammation. 2018 Sep 21;15(1):275. doi: 10.1186/s12974-018-1311-5. J Neuroinflammation. 2018. PMID: 30241539 Free PMC article.
The expression of phospho-IRE1, XBP1, and ATF6 which were the key markers of ER stress were analyzed by immunohistochemistry assay in vivo. ...
The expression of phospho-IRE1, XBP1, and ATF6 which were the key markers of ER stress were analyzed by immunohistochemistry assay in …
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Liu WT, Lv YJ, Yang RC, Fu JY, Liu L, Wang H, Cao Q, Tan C, Chen HC, Wang XR. Liu WT, et al. J Neuroinflammation. 2018 Oct 19;15(1):291. doi: 10.1186/s12974-018-1325-z. J Neuroinflammation. 2018. PMID: 30340642 Free PMC article.
KEGG and gene ontology annotations, ingenuity pathways analysis, and functional experiments were combined to identify the key host molecules involved in the meningitic E. coli-induced tight junction breakdown and neuroinflammatory responses. ...
KEGG and gene ontology annotations, ingenuity pathways analysis, and functional experiments were combined to identify the key host mo …