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LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis.
Yao M, Luo Y, Li H, Liao S, Yu J. Yao M, et al. Mol Neurobiol. 2022 Nov;59(11):6701-6712. doi: 10.1007/s12035-022-03000-4. Epub 2022 Aug 22. Mol Neurobiol. 2022. PMID: 35989413
Tug1 knockdown or overexpression was achieved by intraventricular infusion of AAV-shTug1 in vivo, or transfection of siTug1 and pcDNA3.1-Tug1 in vitro. Neurological function and infarction volume were evaluated. Meanwhile, pyroptosis-associated proteins (IL-1beta, IL-18, N …
Tug1 knockdown or overexpression was achieved by intraventricular infusion of AAV-shTug1 in vivo, or transfection of siTug1 and pcDNA3.1-Tug …
Interleukin 4 improved adipose-derived stem cells engraftment via interacting with fibro/adipogenic progenitors in dystrophic mice.
Li H, Lin J, Wang L, He R, Li J, Chen M, Zhang W, Zhang C. Li H, et al. Cell Mol Life Sci. 2023 Nov 27;80(12):375. doi: 10.1007/s00018-023-05020-2. Cell Mol Life Sci. 2023. PMID: 38010513 Free PMC article.
Adipose-derived stem cells (ADSC) therapy shows promise as an effective treatment for dystrophinopathy. ...The interaction between FAPs and engrafted cells remains unclear. In this study, we used a co-culture system to investigate possible crosstalk between t …
Adipose-derived stem cells (ADSC) therapy shows promise as an effective treatment for dystrophinopathy. ...The interaction bet …
Long-term efficacy and safety of leflunomide combined with low-dose prednisone in treatment of myasthenia gravis: a retrospective study.
Qiu L, Chen P, Ou C, Deng J, Huang Z, Lin Z, Ma Q, Huang X, Yu L, Ran H, Liu W. Qiu L, et al. Acta Neurol Belg. 2024 Feb;124(1):175-182. doi: 10.1007/s13760-023-02367-y. Epub 2023 Sep 1. Acta Neurol Belg. 2024. PMID: 37656361 Review.
METHODS: This retrospective cohort study enrolled MG patients treated with LEF + Pred in our center between 2012 and 2020. We reviewed all the MG patients continuously treated with LEF + Pred for more than 1 year. ...Overall, 63 patients (61.2%) exhibited only minimal mani …
METHODS: This retrospective cohort study enrolled MG patients treated with LEF + Pred in our center between 2012 and 2020. We reviewe …
Antiplatelet therapy may improve the prognosis of patients with moyamoya disease: a 12-year retrospective study.
Luo Y, Cao Z, Ye H, Wu S, Sun X. Luo Y, et al. J Neurol. 2023 Aug;270(8):3876-3884. doi: 10.1007/s00415-023-11702-5. Epub 2023 Apr 27. J Neurol. 2023. PMID: 37106259
OBJECTIVES: The clinical value of antiplatelet therapy (APT) for moyamoya disease (MMD) remains controversial. Our study attempts to clarify the value of APT in this disease. METHODS: We collected basic information, treatment strategies, and prognostic …
OBJECTIVES: The clinical value of antiplatelet therapy (APT) for moyamoya disease (MMD) remains controversial. Our study attem …