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2016 5
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Page 1
The Role of HIF in Immunity and Inflammation.
McGettrick AF, O'Neill LAJ. McGettrick AF, et al. Cell Metab. 2020 Oct 6;32(4):524-536. doi: 10.1016/j.cmet.2020.08.002. Epub 2020 Aug 26. Cell Metab. 2020. PMID: 32853548 Free article. Review.
Mitochondria are the powerhouses of immunity.
Mills EL, Kelly B, O'Neill LAJ. Mills EL, et al. Nat Immunol. 2017 Apr 18;18(5):488-498. doi: 10.1038/ni.3704. Nat Immunol. 2017. PMID: 28418387 Review.
A guide to immunometabolism for immunologists.
O'Neill LA, Kishton RJ, Rathmell J. O'Neill LA, et al. Nat Rev Immunol. 2016 Sep;16(9):553-65. doi: 10.1038/nri.2016.70. Epub 2016 Jul 11. Nat Rev Immunol. 2016. PMID: 27396447 Free PMC article. Review.
Modification of Proteins by Metabolites in Immunity.
Diskin C, Ryan TAJ, O'Neill LAJ. Diskin C, et al. Immunity. 2021 Jan 12;54(1):19-31. doi: 10.1016/j.immuni.2020.09.014. Epub 2020 Nov 20. Immunity. 2021. PMID: 33220233 Free article. Review.
HIF1α and metabolic reprogramming in inflammation.
Corcoran SE, O'Neill LA. Corcoran SE, et al. J Clin Invest. 2016 Oct 3;126(10):3699-3707. doi: 10.1172/JCI84431. Epub 2016 Aug 29. J Clin Invest. 2016. PMID: 27571407 Free PMC article. Review.
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA. Mills EL, et al. Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22. Cell. 2016. PMID: 27667687 Free PMC article.
Krebs Cycle Reborn in Macrophage Immunometabolism.
Ryan DG, O'Neill LAJ. Ryan DG, et al. Annu Rev Immunol. 2020 Apr 26;38:289-313. doi: 10.1146/annurev-immunol-081619-104850. Epub 2020 Jan 27. Annu Rev Immunol. 2020. PMID: 31986069 Review.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
36 results