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2017 1
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2019 2
2021 4
2022 4
2023 1
2024 2

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Page 1
Ocular Drug Delivery: Role of Degradable Polymeric Nanocarriers for Ophthalmic Application.
Tsai CH, Wang PY, Lin IC, Huang H, Liu GS, Tseng CL. Tsai CH, et al. Int J Mol Sci. 2018 Sep 19;19(9):2830. doi: 10.3390/ijms19092830. Int J Mol Sci. 2018. PMID: 30235809 Free PMC article. Review.
In this review, we summarized recent studies on sustained ocular drug/gene delivery and emphasized on the nanocarriers made by biodegradable polymers such as liposome, poly lactic-co-glycolic acid (PLGA), chitosan, and gelatin. Moreover, we discussed the bio-distrib …
In this review, we summarized recent studies on sustained ocular drug/gene delivery and emphasized on the nanocarriers made by biodegradable …
Using Pen-Side Measurable Blood Parameters to Predict or Identify Dystocic Lambing Events.
Redfearn A, McNally J, Brewer H, Doyle E, Schmoelzl S. Redfearn A, et al. Biology (Basel). 2022 Jan 27;11(2):206. doi: 10.3390/biology11020206. Biology (Basel). 2022. PMID: 35205072 Free PMC article.
In a pilot trial, we collected and analysed blood samples in pen-side assays for glucose, lactate, pH, pCO(2), pO(2), base excess, HCO(3), TCO(2), sO(2), lactate, sodium, potassium, chloride, calcium, urea nitrogen, creatinine, haematocrit, haemoglobin and anion gap …
In a pilot trial, we collected and analysed blood samples in pen-side assays for glucose, lactate, pH, pCO(2), pO(2), base excess, HC …
Development of simple, scalable protease production from Botrytis cinerea.
Self RA, Harrison MD, Te'o VS Jr, Van Sluyter S. Self RA, et al. Appl Microbiol Biotechnol. 2022 Mar;106(5-6):2219-2233. doi: 10.1007/s00253-022-11817-1. Epub 2022 Feb 16. Appl Microbiol Biotechnol. 2022. PMID: 35171338 Free PMC article.
Glucan secretion by B. cinerea was minimal in culture medium containing lactose as a carbon source and either lactic or sulfuric acid for pH control. B. cinerea laccases were inactivated by reducing the pH of culture supernatant to 1.5 for 1 h. B. cinerea proteases …
Glucan secretion by B. cinerea was minimal in culture medium containing lactose as a carbon source and either lactic or sulfuric a …
Properties of an acid-tolerant, persistent Cheddar cheese isolate, Lacticaseibacillus paracasei GCRL163.
Shah SS, Al-Naseri A, Rouch D, Bowman JP, Wilson R, Baker AL, Britz ML. Shah SS, et al. J Ind Microbiol Biotechnol. 2021 Dec 23;48(9-10):kuab070. doi: 10.1093/jimb/kuab070. J Ind Microbiol Biotechnol. 2021. PMID: 34555172 Free PMC article.
The distinctive flavours in hard cheeses are attributed largely to the activity of nonstarter lactic acid bacteria (NSLAB) which dominate the cheese matrix during maturation after lactose is consumed. ...When cultured on growth-limiting lactose (0.2%, wt/vol) in the …
The distinctive flavours in hard cheeses are attributed largely to the activity of nonstarter lactic acid bacteria (NSLAB) whi …
Melatonin augments the neuroprotective effects of hypothermia in lambs following perinatal asphyxia.
Aridas JD, Yawno T, Sutherland AE, Nitsos I, Wong FY, Hunt RW, Ditchfield M, Fahey MC, Malhotra A, Wallace EM, Gunn AJ, Jenkin G, Miller SL. Aridas JD, et al. J Pineal Res. 2021 Aug;71(1):e12744. doi: 10.1111/jpi.12744. Epub 2021 Jun 20. J Pineal Res. 2021. PMID: 34032315

Asphyxia induced abnormal brain metabolism on MRS with increased Lactate:NAA (P = .003) and reduced NAA:Choline (P = .005), induced apoptotic and necrotic cell death across gray and white matter brain regions (P < .05), and increased neuroinflammation and oxidative stre

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Asphyxia induced abnormal brain metabolism on MRS with increased Lactate:NAA (P = .003) and reduced NAA:Choline (P = .005), induced a …
The Impact of Pre-Slaughter Stress on Beef Eating Quality.
Loudon KMW, Tarr G, Lean IJ, Polkinghorne R, McGilchrist P, Dunshea FR, Gardner GE, Pethick DW. Loudon KMW, et al. Animals (Basel). 2019 Aug 27;9(9):612. doi: 10.3390/ani9090612. Animals (Basel). 2019. PMID: 31461903 Free PMC article.
However, the mixing response was inconsistent in the eye round muscle and not significant in the other muscles. Plasma glucose and L-lactate indicated a marked acute stress response at slaughter with a small detrimental impact on consumer score. ...
However, the mixing response was inconsistent in the eye round muscle and not significant in the other muscles. Plasma glucose and L-lact …
Effects of Simulated High Altitude on Blood Glucose Levels During Exercise in Individuals With Type 1 Diabetes.
Dugan CW, Maloney SK, Abramoff KJ, Panag SS, Davis EA, Jones TW, Fournier PA. Dugan CW, et al. J Clin Endocrinol Metab. 2022 Apr 19;107(5):1375-1382. doi: 10.1210/clinem/dgab881. J Clin Endocrinol Metab. 2022. PMID: 34935935
Before, during, and after exercise, blood samples were taken to measure glucose, lactate, and insulin levels. Respiratory gases were collected to measure carbohydrate oxidation rates. ...
Before, during, and after exercise, blood samples were taken to measure glucose, lactate, and insulin levels. Respiratory gases were …
Cytocompatibility of electrospun poly-L-lactic acid membranes for Bruch's membrane regeneration using human embryonic stem cell-derived retinal pigment epithelial cells.
Abbasi N, O'Neill H. Abbasi N, et al. J Biomed Mater Res A. 2024 May 10. doi: 10.1002/jbm.a.37736. Online ahead of print. J Biomed Mater Res A. 2024. PMID: 38726752
A carrier membrane is required for cell implantation, which is biocompatible for cell growth and has dimensions and physical properties resembling the Bruch's membrane. Here a nanofiber electrospun poly-L-lactic acid (PLLA) membrane is tested for capacity to support …
A carrier membrane is required for cell implantation, which is biocompatible for cell growth and has dimensions and physical properties rese …
Circulating Tumor DNA Reflects Uveal Melanoma Responses to Protein Kinase C Inhibition.
Park JJ, Diefenbach RJ, Byrne N, Long GV, Scolyer RA, Gray ES, Carlino MS, Rizos H. Park JJ, et al. Cancers (Basel). 2021 Apr 6;13(7):1740. doi: 10.3390/cancers13071740. Cancers (Basel). 2021. PMID: 33917514 Free PMC article.

Plasma ctDNA was assessed using digital droplet PCR (ddPCR) and a custom melanoma gene panel for targeted next generation sequencing (NGS). Baseline ctDNA strongly correlated with baseline lactate dehydrogenase (LDH) (p < 0.001) and baseline disease burden (p = 0.002).

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Plasma ctDNA was assessed using digital droplet PCR (ddPCR) and a custom melanoma gene panel for targeted next generation sequencing (NGS). …
AMP-activated protein kinase activators have compound and concentration-specific effects on brain metabolism.
Achanta LB, Thomas DS, Housley GD, Rae CD. Achanta LB, et al. J Neurochem. 2024 May;168(5):677-692. doi: 10.1111/jnc.15815. Epub 2023 Apr 6. J Neurochem. 2024. PMID: 36977628
Specific direct activation of beta1-containing AMPK isoforms with PF 06409577 resulted in increased Krebs cycle activity, restoring pyruvate metabolism while A769662 increased lactate and alanine production, as well as labelling of citrate and glutamine. ...
Specific direct activation of beta1-containing AMPK isoforms with PF 06409577 resulted in increased Krebs cycle activity, restoring pyruvate …
15 results