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2016 16
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Zika virus pathogenesis and current therapeutic advances.
Mwaliko C, Nyaruaba R, Zhao L, Atoni E, Karungu S, Mwau M, Lavillette D, Xia H, Yuan Z. Mwaliko C, et al. Pathog Glob Health. 2021 Feb;115(1):21-39. doi: 10.1080/20477724.2020.1845005. Epub 2020 Nov 14. Pathog Glob Health. 2021. PMID: 33191867 Free PMC article. Review.
Zika virus (ZIKV) is an emerging arthropod-borne flavivirus that, upon infection, results in teratogenic effects and neurological disorders. ...Likewise, different platforms have been evaluated for the design of vaccines, including DNA, mRNA, peptide, protein …
Zika virus (ZIKV) is an emerging arthropod-borne flavivirus that, upon infection, results in teratogenic effects and ne …
A new coronavirus associated with human respiratory disease in China.
Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, Hu Y, Tao ZW, Tian JH, Pei YY, Yuan ML, Zhang YL, Dai FH, Liu Y, Wang QM, Zheng JJ, Xu L, Holmes EC, Zhang YZ. Wu F, et al. Nature. 2020 Mar;579(7798):265-269. doi: 10.1038/s41586-020-2008-3. Epub 2020 Feb 3. Nature. 2020. PMID: 32015508 Free PMC article.
Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health(1-3). ...Metagenomic RNA sequencing(4) of a sample of bronchoalveolar lavage fluid from the patient identified a new RNA …
Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat …
Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel.
Hao H, Wu S, Lin J, Zheng Z, Zhou Y, Zhang Y, Guo Q, Tian F, Zhao M, Chen Y, Xu X, Hou L, Wang X, Tang R. Hao H, et al. Nat Biomed Eng. 2023 Jul;7(7):928-942. doi: 10.1038/s41551-023-01014-4. Epub 2023 Mar 23. Nat Biomed Eng. 2023. PMID: 36959404
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcutaneous vaccine consisting of live Zika virus electrostatically entrapped in a self-adjuvanting hydrogel recruited immune cells …
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcuta …
Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME.
Zhao Z, Li Q, Ashraf U, Yang M, Zhu W, Gu J, Chen Z, Gu C, Si Y, Cao S, Ye J. Zhao Z, et al. Elife. 2022 Aug 16;11:e73792. doi: 10.7554/eLife.73792. Elife. 2022. PMID: 35972780 Free PMC article.
Zika virus (ZIKV) can be transmitted from mother to fetus during pregnancy, causing adverse fetal outcomes. ...
Zika virus (ZIKV) can be transmitted from mother to fetus during pregnancy, causing adverse fetal outcomes. ...
Zika virus RNA structure controls its unique neurotropism by bipartite binding to Musashi-1.
Chen X, Wang Y, Xu Z, Cheng ML, Ma QQ, Li RT, Wang ZJ, Zhao H, Zuo X, Li XF, Fang X, Qin CF. Chen X, et al. Nat Commun. 2023 Feb 28;14(1):1134. doi: 10.1038/s41467-023-36838-w. Nat Commun. 2023. PMID: 36854751 Free PMC article.
The canonical MSI1 binding site (MBS), A/GU((1-3))AG single-strand motif, is present in many RNA virus genomes, but only Zika virus (ZIKV) genome has been demonstrated to bind MSI1. ...
The canonical MSI1 binding site (MBS), A/GU((1-3))AG single-strand motif, is present in many RNA virus genomes, but only Zika …
PfAgo-Based Zika Virus Detection.
Chen Y, Zhang X, Yang X, Su L, Chen W, Zhao J, Hu Y, Wang Y, Wu Y, Dong Y. Chen Y, et al. Viruses. 2024 Mar 30;16(4):539. doi: 10.3390/v16040539. Viruses. 2024. PMID: 38675882 Free PMC article.
As a mosquito-borne flavivirus, Zika virus (ZIKV) has been identified as a global health threat. ...In addition, the diagnostic findings from the analysis of simulated clinical samples or Zika virus samples using ZIKV-PAND show a complete agreement of …
As a mosquito-borne flavivirus, Zika virus (ZIKV) has been identified as a global health threat. ...In addition, the diagnosti …
Probing Molecular Insights into Zika Virus-Host Interactions.
Lee I, Bos S, Li G, Wang S, Gadea G, Desprès P, Zhao RY. Lee I, et al. Viruses. 2018 May 2;10(5):233. doi: 10.3390/v10050233. Viruses. 2018. PMID: 29724036 Free PMC article. Review.
The recent Zika virus (ZIKV) outbreak in the Americas surprised all of us because of its rapid spread and association with neurologic disorders including fetal microcephaly, brain and ocular anomalies, and Guillain-Barré syndrome. In response to this glob …
The recent Zika virus (ZIKV) outbreak in the Americas surprised all of us because of its rapid spread and association with neu …
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Protein Cell. 2020 Oct;11(10):723-739. doi: 10.1007/s13238-020-00768-w. Epub 2020 Aug 4. Protein Cell. 2020. PMID: 32754890 Free PMC article.
Herein, we identified two potent inhibitors of human DHODH, S312 and S416, with favorable drug-likeness and pharmacokinetic profiles, which all showed broad-spectrum antiviral effects against various RNA viruses, including influenza A virus, Zika virus, Ebola …
Herein, we identified two potent inhibitors of human DHODH, S312 and S416, with favorable drug-likeness and pharmacokinetic profiles, which …
Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection.
Zhang S, He Y, Wu Z, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Gao Q, Sun D, Zhang L, Yu Y, Chen S, Cheng A. Zhang S, et al. Front Immunol. 2023 Jul 13;14:1205002. doi: 10.3389/fimmu.2023.1205002. eCollection 2023. Front Immunol. 2023. PMID: 37520540 Free PMC article. Review.
The genus Flavivirus contains a wide variety of viruses that cause severe disease in humans, including dengue virus, yellow fever virus, Zika virus, West Nile virus, Japanese encephalitis virus and tick-borne encephalitis virus. .. …
The genus Flavivirus contains a wide variety of viruses that cause severe disease in humans, including dengue virus, yellow fever …
Lipid Droplets and Their Participation in Zika Virus Infection.
Qin ZL, Yao QF, Ren H, Zhao P, Qi ZT. Qin ZL, et al. Int J Mol Sci. 2022 Oct 20;23(20):12584. doi: 10.3390/ijms232012584. Int J Mol Sci. 2022. PMID: 36293437 Free PMC article. Review.
Their functions are not limited to serving as neutral lipid reservoirs; they also participate in non-energy storage functions, such as cell lipid metabolism, protection from cell stresses, maintaining protein homeostasis, and regulating nuclear function. During a Zika v …
Their functions are not limited to serving as neutral lipid reservoirs; they also participate in non-energy storage functions, such as cell …
212 results