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2005 1
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608 results

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Diagnosis and management of Guillain-Barré syndrome in ten steps.
Leonhard SE, Mandarakas MR, Gondim FAA, Bateman K, Ferreira MLB, Cornblath DR, van Doorn PA, Dourado ME, Hughes RAC, Islam B, Kusunoki S, Pardo CA, Reisin R, Sejvar JJ, Shahrizaila N, Soares C, Umapathi T, Wang Y, Yiu EM, Willison HJ, Jacobs BC. Leonhard SE, et al. Nat Rev Neurol. 2019 Nov;15(11):671-683. doi: 10.1038/s41582-019-0250-9. Epub 2019 Sep 20. Nat Rev Neurol. 2019. PMID: 31541214 Free PMC article. Review.
The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. ...
The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemi …
Infectious disease in an era of global change.
Baker RE, Mahmud AS, Miller IF, Rajeev M, Rasambainarivo F, Rice BL, Takahashi S, Tatem AJ, Wagner CE, Wang LF, Wesolowski A, Metcalf CJE. Baker RE, et al. Nat Rev Microbiol. 2022 Apr;20(4):193-205. doi: 10.1038/s41579-021-00639-z. Epub 2021 Oct 13. Nat Rev Microbiol. 2022. PMID: 34646006 Free PMC article. Review.
The 2003 severe acute respiratory syndrome coronavirus outbreak, the 2009 swine flu pandemic, the 2012 Middle East respiratory syndrome coronavirus outbreak, the 2013-2016 Ebola virus disease epidemic in West Africa and the 2015 Zika virus disease epidemic al …
The 2003 severe acute respiratory syndrome coronavirus outbreak, the 2009 swine flu pandemic, the 2012 Middle East respiratory syndrome coro …
Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel.
Hao H, Wu S, Lin J, Zheng Z, Zhou Y, Zhang Y, Guo Q, Tian F, Zhao M, Chen Y, Xu X, Hou L, Wang X, Tang R. Hao H, et al. Nat Biomed Eng. 2023 Jul;7(7):928-942. doi: 10.1038/s41551-023-01014-4. Epub 2023 Mar 23. Nat Biomed Eng. 2023. PMID: 36959404
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcutaneous vaccine consisting of live Zika virus electrostatically entrapped in a self-adjuvanting hydrogel recruited immune cells …
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are safe and effective. Here we show that a subcuta …
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin alpha(v)beta(5) Axis.
Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. Zhu Z, et al. Cell Stem Cell. 2020 Feb 6;26(2):187-204.e10. doi: 10.1016/j.stem.2019.11.016. Epub 2020 Jan 16. Cell Stem Cell. 2020. PMID: 31956038 Free PMC article.
Zika virus (ZIKV) causes microcephaly by killing neural precursor cells (NPCs) and other brain cells. ...ZIKV infection was disrupted by genetic targeting of ITGAV or its binding partner ITGB5 and by an antibody specific for integrin alpha(v)beta(5). ...
Zika virus (ZIKV) causes microcephaly by killing neural precursor cells (NPCs) and other brain cells. ...ZIKV infection
Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids.
Wu H, Huang XY, Sun MX, Wang Y, Zhou HY, Tian Y, He B, Li K, Li DY, Wu AP, Wang H, Qin CF. Wu H, et al. Nat Commun. 2023 Sep 8;14(1):5541. doi: 10.1038/s41467-023-41158-0. Nat Commun. 2023. PMID: 37684223 Free PMC article.
Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. ...Overall, our results clearly demonstrate that hTSCs represent the major target cells of ZIKV, and a reduced syncytialization may result from ZIKV infection of early d
Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. ...Overall, our results clearly demo
Axonal variants of Guillain-Barré syndrome: an update.
Shang P, Zhu M, Wang Y, Zheng X, Wu X, Zhu J, Feng J, Zhang HL. Shang P, et al. J Neurol. 2021 Jul;268(7):2402-2419. doi: 10.1007/s00415-020-09742-2. Epub 2020 Mar 5. J Neurol. 2021. PMID: 32140865 Review.
New triggers of the axonal variants of GBS (axonal GBS), such as Zika virus, hepatitis viruses, intravenous administration of ganglioside, vaccination, and surgery, are being identified. ...
New triggers of the axonal variants of GBS (axonal GBS), such as Zika virus, hepatitis viruses, intravenous administration of …
Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation.
Yang W, Liu LB, Liu FL, Wu YH, Zhen ZD, Fan DY, Sheng ZY, Song ZR, Chang JT, Zheng YT, An J, Wang PG. Yang W, et al. Nat Commun. 2023 Apr 29;14(1):2476. doi: 10.1038/s41467-023-38223-z. Nat Commun. 2023. PMID: 37120617 Free PMC article.
Zika virus (ZIKV) is a potential threat to male reproductive health but the mechanisms underlying its influence on testes during ZIKV infection remain obscure. ...C1INH alleviates the pathological change in the testis but deteriorates ZIKV infection in
Zika virus (ZIKV) is a potential threat to male reproductive health but the mechanisms underlying its influence on testes duri
Current Advances in Zika Vaccine Development.
Wang Y, Ling L, Zhang Z, Marin-Lopez A. Wang Y, et al. Vaccines (Basel). 2022 Oct 28;10(11):1816. doi: 10.3390/vaccines10111816. Vaccines (Basel). 2022. PMID: 36366325 Free PMC article. Review.
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in 1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated with a dramatic burden worldwide. ...This review provides a comprehensive summary of
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in 1947 from monkeys and first detecte
CLEC5A mediates Zika virus-induced testicular damage.
Wang HW, Li HH, Wu SC, Tang CK, Yu HY, Chang YC, Sung PS, Liu WL, Su MP, Yu GY, Huang LR, Chen CH, Hsieh SL. Wang HW, et al. J Biomed Sci. 2023 Feb 17;30(1):12. doi: 10.1186/s12929-023-00906-6. J Biomed Sci. 2023. PMID: 36803804 Free PMC article.
BACKGROUND: Zika virus (ZIKV) infection is clinically known to induce testicular swelling, termed orchitis, and potentially impact male sterility, but the underlying mechanisms remain unclear. Previous reports suggested that C-type lectins play important role …
BACKGROUND: Zika virus (ZIKV) infection is clinically known to induce testicular swelling, termed orchitis, and potenti …
The safety and immunogenicity of two Zika virus mRNA vaccine candidates in healthy flavivirus baseline seropositive and seronegative adults: the results of two randomised, placebo-controlled, dose-ranging, phase 1 clinical trials.
Essink B, Chu L, Seger W, Barranco E, Le Cam N, Bennett H, Faughnan V, Pajon R, Paila YD, Bollman B, Wang S, Dooley J, Kalidindi S, Leav B. Essink B, et al. Lancet Infect Dis. 2023 May;23(5):621-633. doi: 10.1016/S1473-3099(22)00764-2. Epub 2023 Jan 19. Lancet Infect Dis. 2023. PMID: 36682364 Clinical Trial.
BACKGROUND: Developing a safe and immunogenic vaccine against Zika virus remains an unmet medical need. We did two phase 1 studies that evaluated the safety and immunogenicity of two mRNA-based Zika virus vaccines (mRNA-1325 and mRNA-1893) in adults. . …
BACKGROUND: Developing a safe and immunogenic vaccine against Zika virus remains an unmet medical need. We did two phase 1 stu …
608 results