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Secretases as therapeutic targets for Alzheimer's disease.
Woo HN, Baik SH, Park JS, Gwon AR, Yang S, Yun YK, Jo DG. Woo HN, et al. Among authors: yun yk. Biochem Biophys Res Commun. 2011 Jan 7;404(1):10-5. doi: 10.1016/j.bbrc.2010.11.132. Epub 2010 Dec 3. Biochem Biophys Res Commun. 2011. PMID: 21130746 Review.
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.
Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE 3rd, Bernier M, Lee J, Markesbery WR, Mattson MP, Jo DG. Gwon AR, et al. Among authors: yun yk. Aging Cell. 2012 Aug;11(4):559-68. doi: 10.1111/j.1474-9726.2012.00817.x. Epub 2012 Apr 9. Aging Cell. 2012. PMID: 22404891 Free PMC article.
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Arumugam TV, Cheng YL, Choi Y, Choi YH, Yang S, Yun YK, Park JS, Yang DK, Thundyil J, Gelderblom M, Karamyan VT, Tang SC, Chan SL, Magnus T, Sobey CG, Jo DG. Arumugam TV, et al. Among authors: yun yk. Mol Pharmacol. 2011 Jul;80(1):23-31. doi: 10.1124/mol.111.071076. Epub 2011 Mar 30. Mol Pharmacol. 2011. PMID: 21450930