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Page 1
Did you mean yuan shuang hu (8 results)?
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J. Zhou C, et al. Among authors: huang y. Signal Transduct Target Ther. 2023 Feb 17;8(1):66. doi: 10.1038/s41392-022-01268-5. Signal Transduct Target Ther. 2023. PMID: 36797256 Free PMC article.
Our results revealed that blocking the FAM83A cascade signaling defines a therapeutic target in human pancreatic cancer....
Our results revealed that blocking the FAM83A cascade signaling defines a therapeutic target in human pancreatic cancer....
Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.
Lee JM, Huang Y, Orth M, Gillis T, Siciliano J, Hong E, Mysore JS, Lucente D, Wheeler VC, Seong IS, McLean ZL, Mills JA, McAllister B, Lobanov SV, Massey TH, Ciosi M, Landwehrmeyer GB, Paulsen JS, Dorsey ER, Shoulson I, Sampaio C, Monckton DG, Kwak S, Holmans P, Jones L, MacDonald ME, Long JD, Gusella JF. Lee JM, et al. Among authors: huang y. Am J Hum Genet. 2022 May 5;109(5):885-899. doi: 10.1016/j.ajhg.2022.03.004. Epub 2022 Mar 23. Am J Hum Genet. 2022. PMID: 35325614 Free PMC article.
These findings indicate that broadened discovery and characterization of HD genetic modifiers based on additional quantitative or qualitative phenotypes offers not only the promise of in-human validated therapeutic targets but also a route to dissecting the mechanisms and …
These findings indicate that broadened discovery and characterization of HD genetic modifiers based on additional quantitative or qualitativ …
Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis.
Ćorović A, Wall C, Nus M, Gopalan D, Huang Y, Imaz M, Zulcinski M, Peverelli M, Uryga A, Lambert J, Bressan D, Maughan RT, Pericleous C, Dubash S, Jordan N, Jayne DR, Hoole SP, Calvert PA, Dean AF, Rassl D, Barwick T, Iles M, Frontini M, Hannon G, Manavaki R, Fryer TD, Aloj L, Graves MJ, Gilbert FJ, Dweck MR, Newby DE, Fayad ZA, Reynolds G, Morgan AW, Aboagye EO, Davenport AP, Jørgensen HF, Mallat Z, Bennett MR, Peters JE, Rudd JHF, Mason JC, Tarkin JM. Ćorović A, et al. Among authors: huang y. J Am Coll Cardiol. 2023 Jan 31;81(4):336-354. doi: 10.1016/j.jacc.2022.10.034. J Am Coll Cardiol. 2023. PMID: 36697134 Free PMC article.
CONCLUSIONS: SST(2) PET/MRI holds major promise for diagnosis and therapeutic monitoring in LVV. (PET Imaging of Giant Cell and Takayasu Arteritis [PITA], NCT04071691; Residual Inflammation and Plaque Progression Long-Term Evaluation [RIPPLE], NCT04073810)....
CONCLUSIONS: SST(2) PET/MRI holds major promise for diagnosis and therapeutic monitoring in LVV. (PET Imaging of Giant Cell and Takay …
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J. Zhou C, et al. Among authors: huang y. Autophagy. 2021 Oct;17(10):3175-3195. doi: 10.1080/15548627.2020.1826689. Epub 2020 Oct 22. Autophagy. 2021. PMID: 32972302 Free PMC article.
Pancreatic cancer is one of the most aggressive tumors associated with a poor clinical prognosis, weakly effective therapeutic options. Therefore, there is a strong impetus to discover new therapeutic targets in pancreatic cancer. ...Our findings suggest that compon …
Pancreatic cancer is one of the most aggressive tumors associated with a poor clinical prognosis, weakly effective therapeutic option …
Nanomedicines for Overcoming Cancer Drug Resistance.
Hu T, Gong H, Xu J, Huang Y, Wu F, He Z. Hu T, et al. Among authors: huang y. Pharmaceutics. 2022 Aug 1;14(8):1606. doi: 10.3390/pharmaceutics14081606. Pharmaceutics. 2022. PMID: 36015232 Free PMC article. Review.
In this respect, novel tumor-targeting nanomedicines offer fairly effective therapeutic strategies for surmounting the various limitations of chemotherapy, targeted therapy and immunotherapy, enabling more precise cancer treatment, more convenient monitoring of treatment a …
In this respect, novel tumor-targeting nanomedicines offer fairly effective therapeutic strategies for surmounting the various limita …
ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer.
Zhang D, Ni QQ, Liang QY, He LL, Qiu BW, Zhang LJ, Mou TY, Le CC, Huang Y, Li TT, Wang SY, Ding YQ, Jiao HL, Ye YP. Zhang D, et al. Among authors: huang y. Oncogene. 2023 Sep;42(38):2841-2853. doi: 10.1038/s41388-023-02806-3. Epub 2023 Aug 17. Oncogene. 2023. PMID: 37591954 Free PMC article.
Together, our findings indicated ASCL2 induces an immune excluded microenvironment by activating CAFs through transcriptionally activating TGFB, and targeting ASCL2 combined with ICIs could present a therapeutic opportunity for MSS CRCs....
Together, our findings indicated ASCL2 induces an immune excluded microenvironment by activating CAFs through transcriptionally activating T …
The Roles of Noncoding RNAs in Systemic Sclerosis.
Liu Y, Cheng L, Zhan H, Li H, Li X, Huang Y, Li Y. Liu Y, et al. Among authors: huang y. Front Immunol. 2022 Apr 8;13:856036. doi: 10.3389/fimmu.2022.856036. eCollection 2022. Front Immunol. 2022. PMID: 35464474 Free PMC article. Review.
Emerging evidence suggests that ncRNAs are abnormally expressed in not only cancer but also autoimmune diseases, such as systemic sclerosis (SSc), and may serve as novel biomarkers and therapeutic targets for the diagnosis and treatment of SSc. However, the functions and u …
Emerging evidence suggests that ncRNAs are abnormally expressed in not only cancer but also autoimmune diseases, such as systemic sclerosis …
225 results