Know your detergents: A case study on detergent background in negative stain electron microscopy.
Gewering T, Januliene D, Ries AB, Moeller A.
Gewering T, et al.
J Struct Biol. 2018 Sep;203(3):242-246. doi: 10.1016/j.jsb.2018.05.008. Epub 2018 May 29.
J Struct Biol. 2018.
PMID: 29852220
Optimization in negative stain can be critical not only for cryo-EM, but also for X-ray crystallography, as highlighted for example by studies on GPCR complexes (Kang et al., 2015; Rasmussen et al., 2012). However, when not done carefully and interpreted correctly, negativ …
Optimization in negative stain can be critical not only for cryo-EM, but also for X-ray crystallography, as highlighted for example by studi …