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Short-Term Therapies for Treatment of Acute and Advanced Heart Failure-Why so Few Drugs Available in Clinical Use, Why Even Fewer in the Pipeline?
Pollesello P, Ben Gal T, Bettex D, Cerny V, Comin-Colet J, Eremenko AA, Farmakis D, Fedele F, Fonseca C, Harjola VP, Herpain A, Heringlake M, Heunks L, Husebye T, Ivancan V, Karason K, Kaul S, Kubica J, Mebazaa A, Mølgaard H, Parissis J, Parkhomenko A, Põder P, Pölzl G, Vrtovec B, Yilmaz MB, Papp Z. Pollesello P, et al. J Clin Med. 2019 Nov 1;8(11):1834. doi: 10.3390/jcm8111834. J Clin Med. 2019. PMID: 31683969 Free PMC article. Review.
Mega-trials in heart failure: effects of dilution in examination of new therapies.
Davison BA, Takagi K, Senger S, Koch G, Metra M, Kimmoun A, Mebazaa A, Voors AA, Nielsen OW, Chioncel O, Pang PS, Greenberg BH, Maggioni AP, Cohen-Solal A, Ertl G, Sato N, Teerlink JR, Filippatos G, Ponikowski P, Gayat E, Edwards C, Cotter G. Davison BA, et al. Eur J Heart Fail. 2020 Sep;22(9):1698-1707. doi: 10.1002/ejhf.1780. Epub 2020 Mar 30. Eur J Heart Fail. 2020. PMID: 32227620 Free article.