Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1783 1
1785 1
1788 1
1808 1
1811 1
1814 2
1823 1
1824 1
1842 2
1843 2
1844 3
1845 2
1847 2
1848 3
1849 1
1850 2
1852 2
1853 1
1854 2
1856 1
1870 1
1871 2
1873 1
1877 2
1878 2
1882 3
1883 3
1884 3
1885 2
1888 2
1889 1
1890 3
1891 3
1892 5
1894 2
1896 4
1898 1
1900 2
1902 1
1903 2
1905 2
1907 1
1908 3
1909 3
1910 1
1911 4
1912 3
1913 5
1914 8
1915 8
1916 10
1917 9
1918 9
1919 10
1920 5
1921 9
1922 13
1923 9
1924 8
1925 4
1926 10
1927 7
1928 5
1929 2
1930 5
1931 6
1932 9
1933 13
1934 6
1935 8
1936 5
1937 4
1938 8
1939 6
1940 6
1941 9
1942 8
1943 7
1944 7
1945 28
1946 53
1947 72
1948 96
1949 75
1950 103
1951 90
1952 116
1953 144
1954 151
1955 151
1956 188
1957 215
1958 225
1959 235
1960 243
1961 261
1962 301
1963 361
1964 388
1965 378
1966 473
1967 533
1968 705
1969 738
1970 871
1971 1314
1972 2656
1973 4675
1974 5525
1975 8711
1976 9223
1977 9322
1978 9692
1979 10570
1980 11972
1981 12511
1982 13814
1983 15870
1984 16881
1985 18031
1986 18954
1987 19352
1988 20106
1989 23274
1990 24522
1991 24703
1992 26146
1993 26293
1994 27263
1995 28249
1996 28858
1997 28182
1998 28111
1999 30015
2000 31684
2001 33287
2002 35186
2003 38132
2004 39841
2005 43059
2006 44055
2007 45097
2008 45288
2009 44399
2010 47215
2011 49837
2012 53130
2013 53715
2014 56076
2015 57179
2016 57522
2017 57814
2018 57697
2019 57567
2020 63001
2021 66591
2022 62558
2023 56572
2024 21538

Text availability

Article attribute

Article type

Publication date

Search Results

1,587,835 results

Results by year

Filters applied: . Clear all
Page 1
Dose translation between laboratory animals and human in preclinical and clinical phases of drug development.
Nair A, Morsy MA, Jacob S. Nair A, et al. Drug Dev Res. 2018 Dec;79(8):373-382. doi: 10.1002/ddr.21461. Epub 2018 Oct 21. Drug Dev Res. 2018. PMID: 30343496
Allometric scaling is the most frequently used approach for dose extrapolation based on normalization of dose-to-body surface area. ...The concept of estimating the first-in-human dose, interspecies scaling between species and the factors influencing the d …
Allometric scaling is the most frequently used approach for dose extrapolation based on normalization of dose-to-body surface …
Preconditioning is hormesis part II: How the conditioning dose mediates protection: Dose optimization within temporal and mechanistic frameworks.
Calabrese EJ. Calabrese EJ. Pharmacol Res. 2016 Aug;110:265-275. doi: 10.1016/j.phrs.2015.12.020. Epub 2015 Dec 31. Pharmacol Res. 2016. PMID: 26748033 Review.
The conditioning dose that demonstrated the largest increase in a mechanism-related conditioning (hormetic) response (i.e., prior to administration of the challenging dose) was the same dose that was optimally protective following the challenging dose. …
The conditioning dose that demonstrated the largest increase in a mechanism-related conditioning (hormetic) response (i.e., prior to …
Oncology dose optimization paradigms: knowledge gained and extrapolated from approved oncology therapeutics.
Mittapalli RK, Guo C, Drescher SK, Yin D. Mittapalli RK, et al. Cancer Chemother Pharmacol. 2022 Sep;90(3):207-216. doi: 10.1007/s00280-022-04444-0. Epub 2022 Aug 14. Cancer Chemother Pharmacol. 2022. PMID: 35965268 Review.
The analysis showed that: (1) the initial label dose was lower than the maximum tolerated dose (MTD) or maximum studied dose (MSD) in Phase 1 for the majority of approved NMEs, and that the MTD approach is no longer the mainstay for dose selection; (2) …
The analysis showed that: (1) the initial label dose was lower than the maximum tolerated dose (MTD) or maximum studied dos …
Volumetric dose extension for isodose tuning.
Ma L, Chen M, Gu X, Lu W. Ma L, et al. Med Phys. 2022 Apr;49(4):2159-2171. doi: 10.1002/mp.15560. Epub 2022 Mar 2. Med Phys. 2022. PMID: 35182074
We adopted extended dose as an approximate dose estimation, and combined it with dose correction strategy to achieve accurate dose tuning. ...In back-end, the output of isodose tuning is obtained by (1) extending dose from the desired isosurface …
We adopted extended dose as an approximate dose estimation, and combined it with dose correction strategy to achieve ac …
Dose in x-ray computed tomography.
Kalender WA. Kalender WA. Phys Med Biol. 2014 Feb 7;59(3):R129-50. doi: 10.1088/0031-9155/59/3/R129. Epub 2014 Jan 17. Phys Med Biol. 2014. PMID: 24434792 Review.
This review aims to present an overview of current concepts for both scanner output metrics and for patient dosimetry and will comment on their strengths and weaknesses. Controversial issues such as the appropriateness of the CT dose index (CTDI) are discussed in detail. A …
This review aims to present an overview of current concepts for both scanner output metrics and for patient dosimetry and will comment on th …
The impact of dose rate on the linear no threshold hypothesis.
Brooks AL. Brooks AL. Chem Biol Interact. 2019 Mar 1;301:68-80. doi: 10.1016/j.cbi.2018.12.007. Epub 2019 Feb 11. Chem Biol Interact. 2019. PMID: 30763551 Free article. Review.
The goal of this manuscript is to define the role of dose rate and dose protraction on the induction of biological changes at all levels of biological organization. ...The importance of dose rate has been recognized almost from the time that radiation was dis …
The goal of this manuscript is to define the role of dose rate and dose protraction on the induction of biological changes at …
Evaluation of TomoTherapy dose calculations with intrafractional motion and motion compensation.
Chao EH, Lucas D, Schnarr E. Chao EH, et al. Med Phys. 2018 Jan;45(1):18-28. doi: 10.1002/mp.12655. Epub 2017 Dec 3. Med Phys. 2018. PMID: 29106739
Film measurements agreed with dose calculations to within 2%/2 mm for 99% of dose points within the 50% isodose line. ...Film measurements agreed with dose calculations to within 2%/2 mm for 98% of dose points within the 50% isodose line. ...
Film measurements agreed with dose calculations to within 2%/2 mm for 99% of dose points within the 50% isodose line. ...Film …
Dose indices: everybody wants a number.
Strauss KJ. Strauss KJ. Pediatr Radiol. 2014 Oct;44 Suppl 3:450-9. doi: 10.1007/s00247-014-3104-z. Epub 2014 Oct 11. Pediatr Radiol. 2014. PMID: 25304704 Review.
This paper discusses the merits and weaknesses of the standard terms that have been developed to quantify CT dose: CT dose indices (CTDI), dose length product (DLP) and effective dose. ...The need for a simple, appropriate method to estimate pediatric …
This paper discusses the merits and weaknesses of the standard terms that have been developed to quantify CT dose: CT dose ind …
Dose Predictions for Drug Design.
Maurer TS, Smith D, Beaumont K, Di L. Maurer TS, et al. J Med Chem. 2020 Jun 25;63(12):6423-6435. doi: 10.1021/acs.jmedchem.9b01365. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31913040
Dose is predicted at many stages in drug discovery and development. Prior to the 1990s, dose prediction was limited to the drug "working" at a reasonable dose and dose regimen in an animal model. ...
Dose is predicted at many stages in drug discovery and development. Prior to the 1990s, dose prediction was limited to the dru …
High coverage and adherence to dose intervals of the national school-based HPV vaccination program in Sweden during 2012-2019.
Wang J, Herweijer E, Nordqvist Kleppe S, Hartwig S, Velicer C, Koro C, Sundström K. Wang J, et al. Prev Med Rep. 2023 Jul 22;35:102342. doi: 10.1016/j.pmedr.2023.102342. eCollection 2023 Oct. Prev Med Rep. 2023. PMID: 37584061 Free PMC article.
Full-dose coverage within a two-dose and three-dose regimen were 73.4% in birth cohorts 2004-2005, and 56.3% in birth cohorts 2000-2001, respectively. ...Among girls receiving a two-dose regimen, 93.0% received the second dose 6-12 months after …
Full-dose coverage within a two-dose and three-dose regimen were 73.4% in birth cohorts 2004-2005, and 56.3% in birth c …
1,587,835 results
You have reached the last available page of results. Please see the User Guide for more information.