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2023 6
2024 2

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Page 1
Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway.
Sun J, Qu H, Ali W, Chen Y, Wang T, Ma Y, Yuan Y, Gu J, Bian J, Liu Z, Zou H. Sun J, et al. Among authors: ali w. Chemosphere. 2023 Dec;344:140372. doi: 10.1016/j.chemosphere.2023.140372. Epub 2023 Oct 4. Chemosphere. 2023. PMID: 37802476
Cd + MPs aggravated Cd- or MPs-induced liver fibrosis and induced liver inflammation. In AML12/HSC-T6 cell in vitro poisoning model, exposure of AML12 cells to Cd + MPs increased the opening of connexin hemichannels and promoted extracellular ATP release. ...
Cd + MPs aggravated Cd- or MPs-induced liver fibrosis and induced liver inflammation. In AML12/HSC-T6 cell in vitro poisoning model, …
Reactive Oxygen Species Control Osteoblast Apoptosis through SIRT1/PGC-1α/P53Lys382 Signaling, Mediating the Onset of Cd-Induced Osteoporosis.
Ran D, Zhou D, Liu G, Ma Y, Ali W, Yu R, Wang Q, Zhao H, Zhu J, Zou H, Liu Z. Ran D, et al. Among authors: ali w. J Agric Food Chem. 2023 Apr 6. doi: 10.1021/acs.jafc.2c08505. Online ahead of print. J Agric Food Chem. 2023. PMID: 37023393
Conversely, overexpression of SIRT1 suppressed Cd-induced ROS release. SIRT1 overexpression in vivo and in vitro dampened PGC-1alpha protein, acetylation of P53 at lysine 382, and caspase-dependent apoptosis. ...
Conversely, overexpression of SIRT1 suppressed Cd-induced ROS release. SIRT1 overexpression in vivo and in vitro dampened PGC-1alpha …
The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro.
Zhu J, Ma Y, Wang J, Wang Y, Ali W, Zou H, Zhao H, Tong X, Song R, Liu Z. Zhu J, et al. Among authors: ali w. Int J Mol Sci. 2023 Jan 12;24(2):1518. doi: 10.3390/ijms24021518. Int J Mol Sci. 2023. PMID: 36675029 Free PMC article.
The previous experiments found that OPG can induce apoptosis of mature osteoclasts in vitro, which can inhibit the activity of mature osteoclasts, thereby exerting its role in protecting bone tissue. ...
The previous experiments found that OPG can induce apoptosis of mature osteoclasts in vitro, which can inhibit the activity of mature …
Melatonin alleviates cadmium-induced nonalcoholic fatty liver disease in ducks by alleviating autophagic flow arrest via PPAR-α and reducing oxidative stress.
Sun J, Bian Y, Ma Y, Ali W, Wang T, Yuan Y, Gu J, Bian J, Liu Z, Zou H. Sun J, et al. Among authors: ali w. Poult Sci. 2023 Aug;102(8):102835. doi: 10.1016/j.psj.2023.102835. Epub 2023 Jun 3. Poult Sci. 2023. PMID: 37343350 Free PMC article.
Interestingly, Mel regulated PPAR-alpha expression and alleviated Cd-induced autophagy blockade. In vitro model, the oil Red O staining, and WB results showed that Mel alleviated Cd-induced lipid accumulation. ...
Interestingly, Mel regulated PPAR-alpha expression and alleviated Cd-induced autophagy blockade. In vitro model, the oil Red O staini …
Interactive mechanism between connexin43 and Cd-induced autophagic flux blockage and gap junctional intercellular communication dysfunction in rat hepatocytes.
Duan Y, Zhang Y, Wang T, Sun J, Ali W, Ma Y, Yuan Y, Gu J, Bian J, Liu Z, Zou H. Duan Y, et al. Among authors: ali w. Heliyon. 2023 Oct 14;9(10):e21052. doi: 10.1016/j.heliyon.2023.e21052. eCollection 2023 Oct. Heliyon. 2023. PMID: 37876489 Free PMC article.
Therefore, the purpose of this study was to investigate the dynamic role of connexin 43 (Cx43) in response to Cd exposure, particularly its impact on gap junctional intercellular communication (GJIC) and autophagy in hepatocytes. To establish an in vitro model of Cd-induce …
Therefore, the purpose of this study was to investigate the dynamic role of connexin 43 (Cx43) in response to Cd exposure, particularly its …
Baicalin and N-acetylcysteine regulate choline metabolism via TFAM to attenuate cadmium-induced liver fibrosis.
Sun J, Chen Y, Wang T, Ali W, Ma Y, Yuan Y, Gu J, Bian J, Liu Z, Zou H. Sun J, et al. Among authors: ali w. Phytomedicine. 2024 Mar;125:155337. doi: 10.1016/j.phymed.2024.155337. Epub 2024 Jan 7. Phytomedicine. 2024. PMID: 38241915
(Methods): We used C57BL/6 J mice, and AML12, and HSC-6T cells to establish in vitro assays and in vivo models. (Results): Metabolomics was used to detect the effect of baicalin and N-Acetylcysteine on liver metabolism, which showed that compared with the control group, th …
(Methods): We used C57BL/6 J mice, and AML12, and HSC-6T cells to establish in vitro assays and in vivo models. (Results): Metabolomi …
Unravelling the potential of Triflusal as an anti-TB repurposed drug by targeting replication protein DciA.
Ali W, Jamal S, Gangwar R, Ahmed F, Pahuja I, Sharma R, Prakash Dwivedi V, Agarwal M, Grover S. Ali W, et al. Microbes Infect. 2024 Mar-Apr;26(3):105284. doi: 10.1016/j.micinf.2023.105284. Epub 2023 Dec 23. Microbes Infect. 2024. PMID: 38145750
The anti-TB activity of drugs was further evaluated under in vitro and ex vivo conditions where Triflusal was observed to have the best possible activity with the MIC of 25 mug/ml. ...
The anti-TB activity of drugs was further evaluated under in vitro and ex vivo conditions where Triflusal was observed to have the be …